A suicide bomber struck the shrine packed with worshippers in a remote village in Jhal Magsi district, about 400 km east of Quetta in Baluchistan province on Thursday.
Senior police officer Mohammad Iqbal said that more than 20 victims were still receiving treatment, some with critical wounds.
The bomber detonated his explosives vest when he was stopped for a routine search by a police officer guarding the shrine. Five children, a woman and two police officers were among those killed.
Daesh claimed responsibility for the attack. It has claimed responsibility for several past attacks in Baluchistan, which has been the scene of a low-level insurgency by Baluch nationalists and separatists demanding more autonomy and a greater share in the region’s natural resources of oil and gas.
Also on Saturday in Baluchistan, at least 13 people were killed and 20 others wounded when a passenger van collided head on with a bus on a highway near the provincial capital of Quetta.
Muqeem Baig, a spokesman for Quetta’s main hospital, said victims were brought to the hospital from the accident site some 32 km south of the city. Such accidents are common in Pakistan, where motorists often disregard traffic rules and safety standards.