Just two soldiers are known to have survived unscathed after the attack on the base in the Chashmo area of Maiwand district in Kandahar province, the defense ministry said in a statement, adding that nine soldiers were wounded and six unaccounted for.
Defense ministry spokesman Dawlat Waziri said the attackers detonated at least one explosive-packed Humvee vehicle and razed the compound in the early morning assault.
The Taliban claimed the ambush in a message to journalists which said all 60 security personnel on the base were killed.
Ten insurgents died, the ministry said.
“We have sent a delegation to assess the situation. The base is under ANA (Afghan National Army) control,” Waziri said.
It was the third suicide and gun attack on a security installation this week and takes the total death toll to more than 100, including soldiers, police and civilians.