Surprising bat genetic trait holds secrets of longevity

Updated 08 February 2018
0

Surprising bat genetic trait holds secrets of longevity

WASHINGTON: Bats are the longest-lived mammals relative to body size, and a species called the greater mouse-eared bat lives especially long. Researchers now have unlocked some of this bat’s longevity secrets, with hints for fighting the effects of aging in people.
Scientists said on Wednesday that unlike in people and most other animals, in this bat species the structures called telomeres located at the end of chromosomes, thread-like strands inside a cell’s nucleus that carry genes determining heredity, do not shorten with age.
Only 19 mammal species are longer-lived than humans relative to body size. Eighteen of them are bats, some living more than four decades. The other is a weird African rodent called a naked mole rat.
The researchers identified two genes in the greater mouse-eared bat that may be responsible for its unique longevity adaptation. These mechanisms could be the focus of future studies on aging, with an eye toward extending healthy lifespans in people, the researchers said.
Telomeres are protective caps at the ends of chromosomes that shorten each time a cell divides. This drives the natural aging process, leading to a breakdown of cells that over time can drive tissue deterioration and eventually death.
“Studying exceptionally long-living mammals that have naturally evolved mechanisms to fight aging is an alternative way to identify the molecular basis of extended ‘health spans,’” said biologist Emma Teeling of University College Dublin in Ireland, one of the study leaders. “Bats are an exciting new model species that will enable us to identify new molecular mechanisms that drive healthy aging.”
The researchers studied 493 individual bats from four species: the greater mouse-eared bat and Bechstein’s bat, both members of the bat genus called Myotis; the greater horseshoe bat; and the common bent-wing bat. Of these, the greater mouse-eared bat had the longest lifespan, about 37 years.
The greater mouse-eared bat and the closely related Bechstein’s bat had telomeres that did not shorten with age, suggesting that Myotis bats share this characteristic. Another Myotis bat, Brandt’s bat, holds the bat longevity record of 41 years.
Based on body size, the greater mouse-eared bat would be predicted to have a maximum lifespan of four years. Its range spans from Western Europe into the Middle East. It preys on large, ground-dwelling creatures like beetles, crickets and spiders.
The research was published in the journal Science Advances.


Startup of the Week: For the love of chocolate

Joudy Delights take part in many of Jeddah’s public events. (Supplied)
Updated 11 December 2018
0

Startup of the Week: For the love of chocolate

  • The store offers additional flavors every month for a limited time

The love for chocolates transcends geographical boundaries, ideologies and cultures. Chocolates are considered a must in times of happiness and to express one’s feelings all across the world.
Saudis also share the love for sweets or chocolates with rest of the world. People in this part of the world do not mind trying different kinds of chocolates — from traditional Arab ones to their European counterparts from as far as Switzerland.
Keeping in view the huge popularity of chocolates in the Kingdom, a Saudi couple decided to launch their own business in 2017. Joudy Delights is a local, home-based specialized chocolate brand that is produced with the highest quality ingredients. The Jeddah-based store is run by 25-year-old housewife Wejdan Shaheen and 29-year-old private sector employee Rakan Nejaim.
Due to stiff competition in this business, it is necessary for an entrepreneur to come up with a novel idea so as to gain an edge over his competitors.
The couple, faced with the same dilemma, chose to introduce a delicious dessert in the market.
“Any new idea needs to go through a lot of experiments. We also had to face the situation when we decided to introduce our famous chocoballs. The finalized version of the product took some time. We had to carefully select the best combination of chocolate and suitable stuffing,” said Nejaim.
Joudy Delights offers milk chocolate, dark chocolate and white chocolate that are filled with two types of different chocolates and two types of biscuits which Shaheen calls their “secret mix.”
The store also offers additional flavors every month for a limited time.
“The milk chocolate chocoballs or what we call our original chocoballs is our most popular product,” said Shaheen.
The number of orders per week differs depending on the season, said Nejaim. “But we receive on an average 65-70 orders per week.”
Joudy Delights take part in many of Jeddah’s public events.
“Many of our clients prefer our products at family gatherings like weddings etc.,” Shaheen said.
The store is planning to expand its reach outside Jeddah, and is likely to introduce a delivery service. Joudy Delights can be found at local Saudi talent shop Crate, located in Al-Salamah district.