Chinese scientist who gene-edited babies fired by university

Chinese scientist He Jiankui claims he used a gene-editing technology known as CRISPR-Cas9 to alter the embryonic genes of twin girls. (AP)
Updated 21 January 2019

Chinese scientist who gene-edited babies fired by university

  • Hundreds of Chinese and international scientists condemned He Jiankui
  • Chinese authorities also denounced He and issued a temporary halt to research activities involving the editing of human genes

SHENZHEN, China: A Chinese scientist responsible for what he said were the world’s first “gene-edited” babies evaded oversight and broke guidelines in a quest for fame and fortune, state media said on Monday, as the university where he worked announced his dismissal.
He Jiankui said in November that he used a gene-editing technology known as CRISPR-Cas9 to alter the embryonic genes of twin girls born that month, sparking an international outcry about the ethics and safety of such research.
Hundreds of Chinese and international scientists condemned He and said any application of gene editing on human embryos for reproductive purposes was unethical.
Chinese authorities also denounced He and issued a temporary halt to research activities involving the editing of human genes.
He had “deliberately evaded oversight” with the intent of creating a gene-edited baby “for the purpose of reproduction,” according to the initial findings of an investigating team set up by the Health Commission of China in southern Guangdong province, Xinhua news agency reported.
He had raised funds himself and privately organized a team of people to carry out the procedure in order to “seek personal fame and profit,” Xinhua said, adding that he had forged ethical review papers in order to enlist volunteers for the procedure.
The safety and efficacy of the technologies He used are unreliable and creating gene-edited babies for reproduction is banned by national decree, the report said.
The Southern University of Science and Technology (SUSTech) in the city of Shenzhen, said in a statement on its website that He had been fired.
“Effective immediately, SUSTech will rescind the work contract with Dr. Jiankui He and terminate any of his teaching and research activities at SUSTech,” the statement said.
The university added the decision came after a preliminary investigation by the Guangdong Province Investigation Task Force.
Neither He nor a representative could be reached for comment on Monday.
He defended his actions at a conference in Hong Kong in November, saying that he was “proud” of what he had done and that gene editing would help protect the girls from being infected with HIV, the virus that causes AIDS.
He’s announcement sparked a debate among Chinese legal scholars over which laws He had technically broken by carrying out the procedure, as well as whether he could be held criminally responsible or not.
Many scholars pointed to a 2003 guideline that bans altered human embryos from being implanted for the purpose of reproduction, and says altered embryos cannot be developed for more than 14 days.
The case files of those involved who are suspected of committing crimes had been sent to the ministry of public security, an unnamed spokesperson for the investigation team was quoted by Xinhua as saying.


“Punch in the gut” as scientists find micro plastic in Arctic ice

Chief Scientist for the Northwest Passage Project Dr. Brice Loose drills an ice core in the Arctic as part of an 18-day icebreaker expedition that took place in July and August 2019 in the Northwest Passage, in a still image taken from a handout video obtained by REUTERS on August 14, 2019. (REUTERS)
Updated 15 August 2019

“Punch in the gut” as scientists find micro plastic in Arctic ice

  • The researchers said the ice they sampled appeared to be at least a year old and had probably drifted into Lancaster Sound from more central regions of the Arctic

LONDON: Tiny pieces of plastic have been found in ice cores drilled in the Arctic by a US-led team of scientists, underscoring the threat the growing form of pollution now poses to marine life in even the remotest waters on the planet.
The researchers used a helicopter to land on ice floes and retrieve the samples during an 18-day icebreaker expedition through the Northwest Passage, the hazardous route linking the Pacific and Atlantic Oceans.
“We had spent weeks looking out at what looks so much like pristine white sea ice floating out on the ocean,” said Jacob Strock, a graduate student researcher at the University of Rhode Island, who conducted an initial onboard analysis of the cores.
“When we look at it up close and we see that it’s all very, very visibly contaminated when you look at it with the right tools — it felt a little bit like a punch in the gut,” Strock told Reuters by telephone.
Strock and his colleagues found the material trapped in ice taken from Lancaster Sound, an isolated stretch of water in the Canadian Arctic, which they had assumed might be relatively sheltered from drifting plastic pollution
The team drew 18 ice cores of up to two meters in length from four locations, and saw visible plastic beads and filaments of various shapes and sizes. The scientists said the findings reinforce the observation that micro plastic pollution appears to concentrate in ice relative to seawater.
“The plastic just jumped out in both its abundance and its scale,” said Brice Loose, an oceanographer at the University of Rhode Island and chief scientist of the expedition, known as the Northwest Passage Project.
The scientists’ dismay is reminiscent of the consternation felt by explorers who found plastic waste in the Pacific Ocean’s Marianas Trench, the deepest place on Earth, during submarine dives earlier this year.
The Northwest Passage Project is primarily focused on investigating the impact of manmade climate change on the Arctic, whose role as the planet’s cooling system is being compromised by the rapid vanishing of summer sea ice.
But the plastic fragments — known as micro plastic — also served to highlight how the waste problem has reached epidemic proportions. The United Nations estimates that 100 million tons of plastic have been dumped in the oceans to date.
The researchers said the ice they sampled appeared to be at least a year old and had probably drifted into Lancaster Sound from more central regions of the Arctic.
The team plans to subject the plastic they retrieved to further analysis to support a broader research effort to understand the damage plastic is doing to fish, seabirds and large ocean mammals such as whales.
Funded by the National Science Foundation and the Heising-Simons Foundation in the United States, the expedition in the Swedish icebreaker The Oden ran from July 18 to Aug. 4 and covered some 2,000 nautical miles.