Malawi becomes 1st nation to immunize kids against malaria

A Health Surveilance Assistant prepares to give a dose of the Malaria Vaccinne into the first recipient on April 23, 2019 at Mitundu Community hospital in Malawi's capital district of Lilongwe on the first day of the Malaria vaccine implementation pilot programme in Malawi aiming to immunise 120,000 children aged two years and under to assess the effectiveness of the pilot vaccine and whether the delivery process is feasible. (AFP)
Updated 24 April 2019
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Malawi becomes 1st nation to immunize kids against malaria

  • The vaccine, known as Mosquirix, was developed by GlaxoSmithKline and was approved by the European Medicines Agency in 2015

LONDON: The World Health Organization says Malawi has become the first country to begin immunizing children against malaria, using the only licensed vaccine to protect against the mosquito-spread disease.
Although the vaccine only protects about one-third of children who are immunized, those who get the shots are likely to have less severe cases of malaria. The parasitic disease kills about 435,000 people every year, the majority of them children under 5 in Africa.
“It’s an imperfect vaccine but it still has the potential to save tens of thousands of lives,” said Alister Craig, dean of biological sciences at the Liverpool School of Tropical Medicine, who is not linked to WHO or vaccine. Craig said immunizing the most vulnerable children during peak malaria seasons could spare many thousands from falling ill or even dying.
The vaccine, known as Mosquirix, was developed by GlaxoSmithKline and was approved by the European Medicines Agency in 2015. A previous trial showed the vaccine was about 30% effective in children who got four doses, but that protection waned over time. Reported side effects include pain, fever and convulsions.
Pedro Alonso, director of WHO’s malaria program, said similar vaccination programs would begin in the coming weeks in Kenya and Ghana, with the aim of reaching about 360,000 children per year across the three countries.
Alonso called the vaccination rollout a “historical moment,” noting that it was significantly more difficult to design a vaccine against a parasite as opposed to a bacterium or virus.
He acknowledged the vaccine was flawed but said the world could not afford to wait for a better option. “We don’t know how long it will take to develop the next-generation vaccine,” he said. “It may be many, many years away.”
In the meantime, he said, the stalled progress against malaria demanded new tools now. Resistance is growing to medicines that treat the disease, while mosquitoes are becoming more resistant to insecticides. In addition, funding for malaria efforts has plateaued in recent years.
It took GSK and partners more than 30 years to develop the vaccine, at a cost of around $1 billion. GSK is donating up to 10 million vaccine doses in the current vaccination initiatives. A company spokesman said GSK is working with partners to secure funding for potentially broader vaccination programs.
Some experts warned the vaccination programs should not divert limited public health funds from inexpensive and proven tools to curb malaria such as bed nets and insecticides.
“This is a bold thing to do, but it’s not a silver bullet,” said Thomas Churcher, a malaria expert at Imperial College London. “As long as using the vaccine doesn’t interfere with other efforts, like the urgent need for new insecticides, it is a good thing to do.”
Craig said one of health officials’ biggest challenges could be convincing parents to bring their children for repeated doses of a vaccine that only protects about a third of children for a limited amount of time.
More commonly used vaccines, like those for polio and measles, work more than 90 percent of the time.
“This malaria vaccine is going to save many lives, even if it is not as good as we would like,” Craig said. “But I hope this will kick-start other research efforts so that the story doesn’t end here.”


Thousands rally in support of Hong Kong police

Updated 20 July 2019
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Thousands rally in support of Hong Kong police

  • Hong Kong has been rocked by more than a month of huge and largely peaceful protests
  • Demonstrators and rights groups have accused riot police of using excessive force, including tear gas and rubber bullets, and public anger against the force is boiling over

HONG KONG: Tens of thousands of people rallied in support of Hong Kong’s police and pro-Beijing leadership on Saturday, a vivid illustration of the polarization coursing through the city after weeks of anti-government demonstrations.
Hong Kong has been rocked by more than a month of huge and largely peaceful protests — as well as a series of separate violent confrontations with police — sparked by a proposed law that would have allowed extraditions to mainland China and other countries.
The bill has since been suspended, but that has done little to quell public anger which has evolved into a wider movement calling for democratic reforms, universal suffrage and a halt to sliding freedoms in the semi-autonomous financial hub.
Saturday’s rally was a moment for the establishment to muster their own supporters.
A predominantly older crowd was joined by families and younger residents, waving Chinese flags and holding banners supporting the police.
“Friends who used violence say they love Hong Kong too, but we absolutely cannot approve of their way of expressing themselves,” said Sunny Wong, 42, who works in insurance.
A 60-year-old woman surnamed Leung said protesters who stormed and vandalized the legislature earlier this month must be held responsible for their acts.
“I really dislike people using violence on others... it was so extreme,” Leung said.
Police estimated a turnout of 103,000 people at the peak of the rally, while local media cited organizers as saying 316,000 attended.
Hong Kong’s police are in the midst of a major reputational crisis.
With no political solution on the table from the city’s pro-Beijing leaders, the police have become enmeshed in a seemingly intractable cycle of clashes with protesters who have continued to hit the streets in huge numbers for six weeks.
Demonstrators and rights groups have accused riot police of using excessive force, including tear gas and rubber bullets, and public anger against the force is boiling over.
Police insist their crowd control responses have been proportionate and point to injured officers as proof that a hardcore minority of protesters mean them harm.
Some of the most violent clashes occurred last Sunday when riot police battled protesters hurling projectiles inside a luxury mall. Some 28 people were injured, including 10 officers.
There is growing frustration among the police force’s exhausted rank and file that neither the city’s leaders, nor Beijing, seem to have any idea how to end the crisis.
Chinese state media and powerful pro-Beijing groups threw their weight behind the pro-police rally.
Saturday’s edition of Hong Kong’s staunchly pro-Beijing newspaper Ta Kung Pao ran a front page encouraging readers to join with the headline: “Kick away the violence.”
It featured a drawing of a large foot kicking over a pro-democracy demonstrator.
Many of those at the rally held aloft large slogans printed on the spread of Wen Wei Po, another stridently pro-Beijing newspaper in the city.
A rally last month by police supporters saw ugly scenes, with many participants hurling insults and scuffling with younger democracy protesters as well as media covering the gathering.
While the pro-government protests have mustered decent crowds, they have paled in comparison with the huge pro-democracy marches that have regularly drawn hundreds of thousands of people.
Anti-government protesters are planning another large march Sunday afternoon and say they have no plan to back down until key demands are met.
Tensions were also raised after police on Saturday said they had discovered a homemade laboratory making high-powered explosives. A 27-year-old man was arrested and pro-independence materials were also discovered.
Under the 1997 handover deal with Britain, China promised to allow Hong Kong to keep key liberties such as its independent judiciary and freedom of speech.
But many say that 50-year deal is already being curtailed, citing the disappearance into mainland custody of dissident booksellers, the disqualification of prominent politicians and the jailing of pro-democracy protest leaders.
Authorities have also resisted calls for the city’s leader to be directly elected by the people.