Japan clones 26 generations from single mouse



AGENCE FRANCE PRESSE

Published — Saturday 9 March 2013

Last update 9 March 2013 3:21 am

| نسخة PDF Print News | A A

TOKYO: Japanese scientists have produced 26 generations of clones from a single mouse, the lead researcher said yesterday, possibly paving the way for the mass replication of valuable livestock.
The team has so far produced 598 mice that are genetic copies of one original creature in an experiment that has so far been going for seven years, said Teruhiko Wakayama of the Riken Center for Developmental Biology.
“This is by far the largest cloning project using a mammal,” he told AFP.
“By applying our study, mass reproduction of prized animals should become possible even after the original animals die,” he said.
Reliable methods for cloning over an extended number of generations could be a boon to farmers who have, for example, a cow that produces a lot of milk, or an animal that is expected to produce particularly high-quality meat.
Natural breeding does not guarantee that an animal’s offspring will have the same qualities, but a clone is an exact copy.
Wakayama has significantly improved on existing capabilities that had a low success rate and tended only to last for a few generations.
The team used a technique called somatic cell nuclear transfer, whereby a cell’s nucleus, which contains the genetic information of the original animal, was inserted into a living egg that had its own nucleus removed.
The egg was then planted in a surrogate who delivered the clone. That cloned result then became a donor for another cell nucleus, which was implanted into a host cell, allowing the cycle to continue.
Overall, the cloned mice have normal biological features, including normal longevity and reproductive capability.
Detailed genetic analysis showed limited abnormalities in non-vital aspects, such as large placenta, but the clone-specific abnormalities neither increased nor decreased over generations of recloning, Wakayama said.
Wakayama’s team has found that use of a certain chemical agent, called a histone deacetylase inhibitor, and other technical improvements allowed recloning to continue for many generations, he said.
“Our results show that repeated iterative recloning is possible,” he said.
“I want to say we should be able to continue this forever. We will continue our study until we see the end of it,” he said.
The study was published in the US-based journal Cell Stem Cell.

What's happening around Saudi Arabia

JEDDAH: The father of the suicide bomber who blew himself up in a mosque in Kuwait has blamed “evil” forces for his son’s behavior.Sounding confused and sad, Sulaiman Al-Gabbaa, the father of Fahad Al-Gabbaa, said: “An evil hand has sent my son to hi...
JEDDAH: The Saudi Traffic Department has denied that it is introducing new license plates for cars.It said hackers posted pictures of the supposedly new license plates on its Twitter account on Sunday. The department said the news, which went viral,...
JEDDAH: The Al-Haramain Train project is described as the largest public transportation project in the Middle East. This vital and strategic project is one of the implementation schemes of the mass expansion of the Saudi railway across the country.Th...
JEDDAH: The number of marriages between expatriates and Saudis has dropped 84 percent to 1,928 since the start of this Islamic year that began on Oct. 24, compared to the same period the previous year.The Ministry of Justice said that there were 12,0...
JEDDAH: The General Authority for Civil Aviation (GACA) launched the idea of a project called Watani to link all parts of the Kingdom by air by beefing up activities at important provincial airports.Capt. Abdul Hakim Badar, assistant vice president a...
JEDDAH: Unofficial marriage is a refuge for a divorced mother to lead a married life while keeping her children in her custody but without the knowledge of the former husband who could demand the custody of the children if he learned about the ex-wif...
JEDDAH: Makkah’s health department has set up a committee to verify the sick leave certificates of employees.The department stated it would apply government regulations on sick leave, which includes people providing the address of the facilities wher...
RIYADH: The directorate of roads and transport has registered 20 cases of violations worth SR24,500 in Al-Qassim, where the transport ministry continued its surveillance drive against the companies in the transport business.According to the directora...
RIYADH: The implementation of an integrated health plan to combat MERS has resulted in a sharp drop in cases, with only one out of 736 samples testing positive for the contagion in the Kingdom in the last six days. Health Ministry spokesman Dr. Khal...
RIYADH: Muslims must cut traditionally high electricity use during Ramadan in line with the principles of austerity and self-control they are supposed to adopt in this month, economists say.Economist Al-Sadeq Idris said energy use increases during Ra...
JEDDAH: The Ministry of Commerce and Industry will begin next Tuesday to check whether companies are complying with new laws requiring them to place proper price labels on all their products.It is mandatory for companies to stop using phrases such as...
RIYADH: Minister of Islamic Affairs Saleh Al-Asheikh chaired the first meeting with Yemeni scholars to exchange ideas on how to strengthen their role in restoring peace in their country.The first Saudi-Yemen scholars meeting, dubbed the “outreach sch...
RIYADH: To cope with the growing number of applicants (boys and girls) at technical colleges that reached 126,023 last year, a state-run organization launched an online unified portal to ease the enrolment procedures.According to the Technical and V...
RIYADH: A senior government official from Dhaka, who visited Riyadh last week, has sorted out technical issues to expedite issuing 1.5 million machine readable passports (MRP) to Bangladeshi expatriates in the Kingdom. Information and Communication T...
JEDDAH: Jeddah municipality is keen to provide health and food security to residents and visitors of the city, and they are continually conducting inspections of food stores, restaurants, markets and food storage facilities to avoid any violations by...

Stay Connected

Facebook