Surprising bat genetic trait holds secrets of longevity

Updated 08 February 2018
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Surprising bat genetic trait holds secrets of longevity

WASHINGTON: Bats are the longest-lived mammals relative to body size, and a species called the greater mouse-eared bat lives especially long. Researchers now have unlocked some of this bat’s longevity secrets, with hints for fighting the effects of aging in people.
Scientists said on Wednesday that unlike in people and most other animals, in this bat species the structures called telomeres located at the end of chromosomes, thread-like strands inside a cell’s nucleus that carry genes determining heredity, do not shorten with age.
Only 19 mammal species are longer-lived than humans relative to body size. Eighteen of them are bats, some living more than four decades. The other is a weird African rodent called a naked mole rat.
The researchers identified two genes in the greater mouse-eared bat that may be responsible for its unique longevity adaptation. These mechanisms could be the focus of future studies on aging, with an eye toward extending healthy lifespans in people, the researchers said.
Telomeres are protective caps at the ends of chromosomes that shorten each time a cell divides. This drives the natural aging process, leading to a breakdown of cells that over time can drive tissue deterioration and eventually death.
“Studying exceptionally long-living mammals that have naturally evolved mechanisms to fight aging is an alternative way to identify the molecular basis of extended ‘health spans,’” said biologist Emma Teeling of University College Dublin in Ireland, one of the study leaders. “Bats are an exciting new model species that will enable us to identify new molecular mechanisms that drive healthy aging.”
The researchers studied 493 individual bats from four species: the greater mouse-eared bat and Bechstein’s bat, both members of the bat genus called Myotis; the greater horseshoe bat; and the common bent-wing bat. Of these, the greater mouse-eared bat had the longest lifespan, about 37 years.
The greater mouse-eared bat and the closely related Bechstein’s bat had telomeres that did not shorten with age, suggesting that Myotis bats share this characteristic. Another Myotis bat, Brandt’s bat, holds the bat longevity record of 41 years.
Based on body size, the greater mouse-eared bat would be predicted to have a maximum lifespan of four years. Its range spans from Western Europe into the Middle East. It preys on large, ground-dwelling creatures like beetles, crickets and spiders.
The research was published in the journal Science Advances.


Startup of the Week: Protein Laboratory: Making healthy eating fun and easy

Updated 17 September 2019

Startup of the Week: Protein Laboratory: Making healthy eating fun and easy

  • And with growing health awareness, many Saudis are switching over to more nutritious dietary habits

JEDDAH: An enterprising Saudi family is aiming to take the world by storm with its scientific approach to healthy eating.

The Bogari’s newly opened Protein Laboratory restaurant in Jeddah is the brainchild of brothers Ahmed, Hussain and Hassan.

The three doctors got the inspiration for their startup from hospital laboratories while studying in medical school, and with the help of their parents set about establishing their innovative culinary venture.

In recent years the health and fitness fad has become a flourishing business sector in the Kingdom, which has witnessed a dramatic rise in the number of gyms and fitness centers.

And with growing health awareness, many Saudis are switching over to more nutritious dietary habits. However, eating clean can be a challenge for those with busy, modern lifestyles who do not have the time to prepare meals.

Enter the Protein Laboratory, opened to add fun to the idea of healthy food. “We wanted to reintroduce the concept of healthy food to the Saudi health and fitness community,” Ahmed, 27, told Arab News.

“We believe that healthy food does not have to be boring and achieving your goal of fat loss can actually satisfy your taste buds and leave you happily full at the same time.

“We are planning to expand in Jeddah and Makkah to help more people achieve their fitness targets while enjoying tasty food, and we are aiming to be recognized globally,” he said.

The trio started planning their enterprise while studying at medical college but credit their parents’ support for helping turn their vision into a successful business launch.

Their father guided them in setting up the company and their mother took responsibility for the restaurant’s kitchen, playing a major role in developing recipes and supervising operations.

The brothers’ association with the field of medicine also helped them in their efforts. Ahmed was first inspired by hospital laboratories and the way researchers worked on minor details to get the best possible results.

“The long counters, glass walls, and test tubes are what I liked the most, in addition to the complete transparency of the place. It is exactly how I wanted our restaurant to be. Everything to be prepared and cooked just in front of the customer with a high level of attention to detail,” he added.

The idea behind the name Protein Laboratory was to ensure customers had the option to select, mix and create ingredients according to their taste or preference.

“Customers can order their meals according to their nutritional needs and preferences, starting with selecting the protein base, cooking method, side dishes, the sauce and portion of the meal’s components in grams.”

Ahmed said: “We use the healthiest cooking methods possible. We don’t use frozen meat; we blend our own spices and make sure everything is always made in the healthiest way.”

The brothers and their mother work like scientists. “We spent one year testing ingredients and creating healthy recipes. We had only one goal in mind: High protein in a healthy meal and a portion that could help us and others to stay healthy while still eating the food we desired with higher quality and better taste,” Ahmed added.

Their lab salad dish includes more than 20 organic ingredients high in protein, fiber and antioxidants. The restaurant’s burger has only 396 calories, and one of their best-selling desserts is a sugar-free banana pancake.

“We aim to make our prices within everyone’s reach,” Ahmed said.

One of the services offered by the restaurant is subscription to a meal plan drawn up according to the nutritional needs of the customer and delivered to their workplace or home.

Protein Laboratory is located in Helmi Kutbi Street, in Jeddah’s Al-Zahra district and can be followed on Instagram @proteinlabsa.