Thomas passed for 288 yards and Maehl had eight catches for a career-high 145 yards for the high-powered Ducks, who racked up 599 total yards in yet another barn-burning offensive performance.
Matt Barkley passed for 263 yards and Marc Tyler rushed for two scores for the Trojans.
At Oxford, Mississippi, Cam Newton caught a touchdown pass, to go along with the two TD passes he threw, and Mike Dyer ran for 180 yards for Auburn.
The Tigers are ranked atop the BCS standings for the first time.
At Las Vegas, Andy Dalton threw for 252 yards and two touchdowns as TCU dominated defensively again to stay undefeated.
TCU, which was also fourth in the BCS standings, heads into a huge conference showdown at No. 8 Utah, having allowed 16 points in the last five games.
Ed Wesley ran 64 yards on 13 carries with a touchdown and Dalton finished 16 of 23 with no interceptions.
At Iowa City, Iowa, Ricky Stanzi threw three touchdown passes as Iowa handed Michigan State its first loss decisively.
Adam Robinson added a pair of touchdowns for the charged-up Hawkeyes, who rolled out to a 30-0 halftime lead and dealt a crushing blow to the Spartans' national title hopes.
At Lincoln Nebraska, Roy Helu Jr. rushed for a school-record 307 yards as Nebraska knocked Missouri from the unbeatens.
The Cornhuskers held off the Tigers after building a 24-0 lead and moved into a first-place tie with them in the Big 12 North. Nebraska earned the inside track to the division title by winning the head-to-head meeting.
At Minneapolis, Terrelle Pryor threw for 222 yards and two touchdowns, and Dan Herron rushed for 114 yards and another score in the first half to lead Ohio State.
Pryor completed 18 of 22 passes and also rushed for 55 yards and a touchdown for the Buckeyes (8-1, 4-1 Big Ten), who are trying to ram their way back into the national championship picture.
Air Force Academy, Colorado, Utah's defense forced five turnovers and stopped the Falcons twice on downs in the final quarter to win heading into its big game with TCU next weekend.
Safety Greg Bird came up with one big hit after another and Eddie Wide scored twice as the Utes ran their record to 8-0 for the third time in the last seven years.
At Seattle, Andrew Luck ran for one score and threw for another as No. 13 Stanford scored touchdowns on its first four possessions.
Facing Washington quarterback Jake Locker in a matchup of touted NFL draft prospects, Luck was easily more impressive. The Stanford sophomore completed 19 of 26 passes for 192 yards and added another 92 yards rushing.
Stepfan Taylor ran for 97 yards and two touchdowns for Stanford.
At Pasadena, California, backup Matt Scott passed for a career-high 319 yards as Arizona held off UCLA.
Scott, playing for injured starter Nick Foles (knee), was 24 of 36 with one interception and one touchdown. The junior also carried 12 times for 71 yards.
At Columbia, South Carolina, Alshon Jeffery's 70-yard touchdown catch broke a fourth-quarter tie and kept South Carolina in control of the SEC East.
The Vols had rallied back from a 14-point deficit on a pair of touchdown passes from backup quarterback Tyler Bray to tie the game at 24.
At Fayeteville, Arkansas, Ryan Mallett threw for a school-record 409 yards as Arkansas beat Vanderbilt.
Mallett topped his own record of 408 yards, set last year against Georgia, and finished 27 of 44 as the Razorbacks won their second straight game.
At Manhattan, Kansas, Brandon Weeden threw two touchdown passes as No. 20 Oklahoma State's high-powered offense overcame the absence of star wide receiver Justin Blackmon to beat Kansas State.
Blackmon, suspended for the game after being arrested on a misdemeanor drink driving charge, left the Cowboys without the nation's leader in receiving yards per game, total receiving yards, scoring and touchdown catches.
At Charlottesville, Virginia, Virginia intercepted Miami's backup quarterbacks four times after Jacory Harris was hurt and pulled off the upset.
Virginia, which had lost nine straight conference games, knocked Harris from the game on a huge hit by John-Kevin Dolce in the second quarter with the score still 0-0.
At Starkville, Mississippi, Vick Ballard rushed for 103 yards and a touchdown as Mississippi State relied on its running game and defense.
The Wildcats threatened to tie the game in the final minute, but Mike Hartline's pass was intercepted by Johnthan Banks at the goal line to seal a sixth straight victory for Mississippi State - its longest streak since 1999.
At Austin, Texas, Robert Griffin III passed for two touchdowns and ran for another and Baylor beat Texas for the first time since 1997.
Baylor trailed 19-10 early in the third quarter before Jay Finley ran 69 yards for a touchdown. Griffin then scored on a 1-yard touchdown run and hit Kendall Wright with a 30-yard scoring pass in the fourth.
