O’Sullivan (1-0) was starting in place of Scott Kazmir , who was put on the disabled list Sunday because of shoulder fatigue. Called up from Triple-A Salt Lake earlier Tuesday, the right-hander retired 12 in a row after giving up two runs in the first inning. In six innings, he allowed two hits, three walks and struck out four.

Izturis homered in his first game back after missing 27 with a left forearm strain. His fourth-inning drive gave the Angels a 4-2 lead. Napoli connected in the fifth, and Matsui, a former Yankee, homered in the seventh.

Phil Hughes (11-3), making his first start since getting the loss in the All-Star game at Anaheim last Tuesday, gave up a season-high six runs.

Athletics 5  Red Sox 4, 10 innings: At Oakland, California, Kevin Kouzmanoff hit a two-out RBI single in the 10th inning to cap Oakland’s rally.

The Red Sox took a 4-0 lead in the second inning and the A’s tied it in the third. Neither team scored again until the 10th.

Daric Barton singled with one out and advanced to second when plate umpire Bob Davidson called a balk on Ramon Ramirez (0-3). The Red Sox then intentionally walked Kurt Suzuki before Dustin Richardson came in and struck out Adam Rosales .

Orioles 11  Tampa Bay 10, 10 innings: At Baltimore, Baltimore’s Julio Lugo singled in the winning run in the 13th inning, and the teams combined for seven solo home runs.

The Orioles trailed by four runs in the seventh and 10-9 in the 12th before rallying to end a four-game skid.

Cesar Izturis led off the 13th by drawing a walk from Lance Cormier (3-2). After a sacrifice, Lugo grounded a single inside the first-base line to bring home Izturis.

Luke Scott , Ty Wigginton and Adam Jones hit successive homers off Matt Garza in the second inning, the first the Orioles went back-to-back-to-back for the first time since Sept. 5, 1995 — the night Cal Ripken Jr. tied Lou Gehrig’s record of playing in 2,130 consecutive games.

Koji Uehara (1-0), the last of six Baltimore pitchers, got the win with 1 1-3 innings of one-hit relief.

White Sox 4  Mariners 0: At Seattle, John Danks combined with two relievers on a two-hitter and Alexei Ramirez homered for Chicago.

Danks (10-7) allowed Casey Kotchman’s infield single in the second and Ichiro Suzuki’s two-out single in the eighth on his final pitch of the night. He struck out eight and walked four.

Chicago increased its lead in the AL Central to a season-high 3 1/2 games over Detroit and Minnesota.

Bobby Jenks pitched a perfect ninth in his first appearance since he failed to record an out on Sunday, when he was charged with four runs in a loss at Minnesota.

Rangers 8  Tigers 0: At Detroit, Tommy Hunter pitched seven scoreless innings, and Josh Hamilton and Ian Kinsler homered for Texas.

The AL West-leading Rangers are 5-1 since the All-Star break.

Hunter became the first Ranger to start a season 7-0, pitching only as a starter. He gave up three hits and two walks.

Detroit has lost a season-high seven straight. Armando Galarraga (3-3) gave up four runs and nine hits in 7 1-3 innings.

Indians 4 Twins 3: At Minneapolis, Travis Hafner had two hits and the go-ahead RBI in the eighth inning, and Justin Masterson allowed three runs and seven hits in 6 1-3 innings for Cleveland.

Shelley Duncan added a bases-loaded double in the sixth for the Indians, who are 6-0 since the All-Star break.

Rafael Perez (3-0) picked up the win in relief of Masterson and Chris Perez earned his ninth save.

The Twins trailed 3-1 after Duncan’s double in the sixth, but tied it on a bloop single by Denard Span and a roller through the left side from Orlando Hudson .

Jose Mijares (1-1) walked leadoff man Carlos Santana before Hafner ripped a double to take the lead.

Blue Jays 13 Royals 1: At Kansas City, Missouri, Toronto’s Jose Bautista hit his major league-leading 26th home run and drove in five runs to back Jesse Litsch , who picked up his first victory since 2008.

The Blue Jays have won four of their past five games, while the Royals have lost seven of eight.

Bautista hit a two-run homer in the first inning. He has homered in six of his last 13 games. His single in the second scored John Buck , who had three doubles.

Bautista’s double in a five-run eighth gave him five RBIs to match his career high.