Sabathia (20-6) leads the majors in victories. He twice finished seasons with 19 wins, and succeeded this year in his third try at No. 20.

Sabathia already had a Cy Young pitching award, a World Series championship and several All-Star selections to his credit over 10 seasons. Winning 20 games was about the only thing missing on his pitching resume.

The big lefty allowed three runs on seven hits over seven innings for the American League East leaders. Sabathia, denied the milestone win in a home loss to the Orioles on Sept. 7, walked one and struck out four, improving to 14-2 all-time against Baltimore.

Robinson Cano and Curtis Granderson homered for the Yankees. Cano's two-run shot put the second baseman at 101 RBIs. That gave the Yankees three infielders with 100 or more RBIs in a single season for the first time in franchise history - first baseman Mark Teixeira and third baseman Alex Rodriguez previously reached the mark.

Jeremy Guthrie (10-14) took the loss.

At St. Petersburg, Florida, Carlos Pena hit a tying single with two outs in the ninth inning for Tampa Bay, then shortstop Brandon Wood's throwing error with two outs in the 10th lifted the Rays over Los Angeles.

The Rays stayed one-half game behind New York in the AL East, and continued to hold a sizable lead over Boston in the wild-card race.

Reid Brignac opened the Rays 10th with a double off Bobby Cassevah (0-2), and pinch runner Jason Bartlett went on third on John Jaso's grounder.

Slumping Ben Zobrist walked, Carl Crawford popped out and Evan Longoria was intentionally walked to load the bases.

Willy Aybar hit a grounder on a full-count pitch up the middle that Wood fielded, but he made a wild throw.

At Boston, Jose Batista hit his major league-leading 49th homer, extending his own club record set one night earlier, as Toronto beat Boston.

Batista's homer in the first inning sailed over the Green Monster seats and into a parking lot across the street. The Blue Jays' slugger established the franchise home run record in Friday's win. George Bell held the previous mark with 47, set in 1987.

Ricky Romero (13-9) pitched six innings for the win. Kevin Gregg got three outs for his 33rd save.

At Minneapolis, rookie Danny Valencia hit a tiebreaking three-run homer in the sixth inning, sending Kevin Slowey and AL Central-leading Minnesota over Oakland.

The Twins' magic number for clinching the division is five. They lead Chicago by 10 games.

Slowey (13-6) set a career high for wins, giving up two runs and five hits in 6 2-3 innings. Matt Capps earned his 40th save and 13th in 15 chances since coming to Minnesota.

Landon Powell homered and doubled for Oakland. Rookie Chris Carter kept struggling, going 0 for 2 with a pair of strikeouts - he is 0 for 29 with 13 whiffs since making his major league debut this season.

At Chicago, pinch-hitter Scott Sizemore connected for a three-run homer in the eighth inning to lift Justin Verlander and Detroit over Chicago.

Chicago lost its fifth in a row.

Verlander (17-8) pitched a six-hitter and struck out eight. He struggled in only one inning, giving up three runs in the fifth.

Sizemore, batting for starting second baseman Will Rhymes, hit a tiebreaking home run with two outs.

At Seattle, Cliff Lee shut down his former teammates for eight innings in his first start in Seattle since a July trade.

Lee (12-8) allowed six hits and struck out eight for his second consecutive win after three losses and a no decision. Lee improved to 4-5 with the Rangers as they close in on their first postseason berth since 1999.

Bengie Molina had three hits and two RBIs and Jeff Francoeur hit a two-run double to lead the AL West-leading Rangers.

Seattle's Franklin Gutierrez hit a solo homer in the seventh.

At Kansas City, Missouri, Matt LaPorta's first career grand slam powered Cleveland past Kansas City on a long, stormy night that included four rain delays totaling 3 hours and 40 minutes.

LaPorta's grand slam off Sean O'Sullivan (2-6) gave Cleveland a 5-0 lead in the fourth. Then Jai Miller and Mike Aviles hit two-run homers for Kansas City in the fifth off Justin Germano.

The rain delay in the top of the fourth lasted only 2 minutes. The stoppage after the sixth was 1 hour, 39 minutes.