Koa Misi recovered Favre's fumble in the end zone for a touchdown and Brian Hartline scored on a 5-yard pass from Chad Henne to keep the Dolphins (2-0) undefeated.

The 40-year-old Favre was 19 of 28 for 197 yards. He threw two interceptions at home all of last season, but topped that total in the home opener.

Peterson rushed for 145 yards and a touchdown for the Vikings (0-2), who forced two fumbles in a mistake-filled game.

At East Rutherford, New Jersey, Mark Sanchez threw a career-high three touchdown passes as the Jets held off New England despite losing Darrelle Revis.

Sanchez completed a career-high 21 passes on 30 attempts for 220 yards and connected with Braylon Edwards, Jerricho Cotchery and Dustin Keller for scores.

: At Detroit, Michael Vick's first start in four years was a winning one, with the quarterback throwing two touchdown passes in the first half before Philadelphia held off a late rally.

LeSean McCoy gave the Eagles (1-1) an 18-point lead with his third score with 6:17 left. The Lions (0-2) pulled within three points and recovered an onside kick with 1:50 left, but turned the ball over on downs without gaining a yard.

Vick, starting for Kevin Kolb (concussion), missed two seasons while serving an 18-month sentence for his role in a dogfighting operation and played sparingly last year. He hit 21 of 34 passes for 284 yards, ran for 37 yards.

At Landover, Maryland, Neil Rackers kicked a 35-yard field goal with 3:24 left in overtime, and Matt Schaub passed for a franchise-record 497 yards as Houston won again.

Schaub completed 38 of 52 passes with three touchdowns and one interception for the Texans, who have won their first two games of the season for only the second time in team history.

At Indianapolis, Peyton Manning threw for three touchdowns to easily outplay younger brother Eli as Indianapolis routed the New York.

In the second NFL meeting of siblings as starting quarterbacks, Peyton Manning got lots of help from his running game and the Colts defense. Joseph Addai rushed for 92 yards, Donald Brown added 69 and Indianapolis (1-1) forced Eli Manning to fumble twice, resulting in 14 points.

At Arlington, Texas, Jay Cutler threw three touchdown passes to lead Chicago to its first win-win start since its Super Bowl season in 2006.

Dallas blew a chance to level the game at 20-all when David Buehler badly missed a 44-yard field goal with 7:23 left. Chicago immediately drove for a lead-extending touchdown. Buehler made a 48-yarder with 1:17 left, but the Bears caught an onside kick.

At Nashville, Tennessee, Antonio Brown scored from an 89-yard kickoff return to open the game as Pittsburgh forced seven turnovers.

Dennis Dixon hurt his left knee and was replaced by Charlie Batch, but the Steelers (2-0) swarmed the Titans (1-1) and came up with four sacks and forced the most turnovers by Tennessee since 2000.

At Green Bay, Clay Matthews' three sacks led a dominant defense, while Aaron Rodgers threw for two TDs and scrambled for another for the Packers.

Rodgers threw for 255 yards, with touchdowns to Donald Driver and James Jones. He also ran 9 yards for a score.

At Cleveland, Brandon Flowers returned an interception for a touchdown and Ryan Succop kicked three field goals as Kansas City converted a late fourth-down gamble by coach Todd Haley for the win.

Jerome Harrison, who ran for 286 yards against the Chiefs last year, was held to 33 yards on 16 carries.

At Atlanta, Matt Ryan matched a career high with three touchdown passes, and third-string running back Jason Snelling rushed for 129 yards and scored three times for Atlanta.

Snelling took over after the top two backs, Michael Turner and Jerious Norwood, went out with injuries. The replacement carried 24 times for 129 yards, including a pair of touchdowns. He also hauled in a 19-yard touchdown pass from Ryan.

At Cincinnati, Mike Nugent kicked a career-high five field goals, two of them in the closing minutes, as the Bengals held on to win.

Cincinnati (1-1) won the division last season with a 6-0 record. New kicker extended the Bengals' streak of division wins to a club-record eight straight.

The Ravens (1-1) couldn't pull one out despite another brilliant day by their defense, which hasn't allowed a touchdown in its past 10 quarters since the playoffs.

At Denver, Kyle Orton threw for 307 yards and two TD passes and top draft pick Demaryius Thomas caught eight passes for 97 yards and a touchdown for Denver.

Orton also threw one to Eddie Royal - his first TD catch since 2008 as the Broncos dominated the Seahawks (1-1).

At Charlotte, North Carolina, Josh Freeman threw for 178 yards and two touchdowns and Tampa Bay is off to its first 2-0 start in five years.

A year after opening 0-7 and just over nine months removed from Freeman's five-interception nightmare against Carolina, the second-year quarterback avoided any big mistakes.

At San Diego, Philip Rivers threw for 334 yards and three touchdowns, and San Diego forced six turnovers.

At Oakland, Bruce Gradkowski replaced an ineffective Jason Campbell after halftime and led the Raiders to three scoring drives.

Gradkowski threw a 4-yard touchdown pass to Louis Murphy, Darren McFadden ran for 145 yards and Sebastian Janikowski kicked three field goals to give Oakland (1-1) its first win in a home opener since 2004.