Clinton's remarks came in an interview with Lebanon's An-Nahar newspaper, published Friday. It followed a threat by Hezbollah's leader Hassan Nasrallah who on Thursday said his group will "cut the hand" of anyone who tries to arrest its members for the 2005 assassination of Rafik Hariri.

The Netherlands-based tribunal is expected to issue indictments soon, and speculation that members of the Hezbollah could be targeted has fueled fears of violence and a political crisis in the country. Nasrallah, who claims the court is biased, has said he expects members of his group to be indicted.

"Hezbollah should know that resorting once again to violence in Lebanon runs completely counter to the interests of the Lebanese people, the interests of the region, and of the United States," Clinton said. "They should also know that if the goal of violence is to stop the tribunal, it won't work," she added.

Hariri, Lebanon's most prominent politician after a 15-year civil war ended in 1990, was killed by a truck bombing that ushered in major political upheaval in the country. Immediately after the assassination, suspicion fell on Damascus, leading to massive protests that led to the end of Syria's nearly 30-year military presence in Lebanon.

Damascus and Hezbollah have denied having any role in the killing.

Nasrallah has also urged Lebanese not to cooperate with the probe. He says the court is an "Israeli project" and poisoned by "false witnesses" who misled the investigation.

Clinton said "intimidation or threats" from Hezbollah should not be tolerated. "The problem in Lebanon is not the Special Tribunal for Lebanon. The problem is that some are threatening violence in order to try to stop justice," she said in the interview.

The rising tensions in Lebanon are also affecting America's relations with Syria. Clinton said Syria's behavior "has not met our hopes and expectations" over the past 20 months.

In October, the American ambassador to the United Nations accused Syria of working with Iran and Hezbollah to destabilize Lebanon.