LSU was without star cornerback Tyrann Mathieu, leading rusher Spencer Ware and defensive back Tharold Simon — all suspended one game for violating the team’s drug policy.

Randle finished with five receptions for 106 yards. Lee was 14 of 20 for 165 yards and two touchdowns, while Jefferson completed two of three passes for 54 yards.

LSU gained 174 yards on the ground, led by Michael Ford with 12 rushes for 82 yards.

In Tuscaloosa, Alabama, AJ McCarron passed for 284 yards and a touchdown and ran for another score to lead Alabama to a second-half surge.

The Crimson Tide scored on its first five possessions after halftime to turn a close game into a blowout. The Tide outgained the Volunteers 280-41 in the second half and didn’t allow a first down.

Alabama won its eighth game of the season and next faces No. 1 LSU at home on Nov. 5.

In Norman, Oklahoma, Seth Doege threw for 441 yards and connected with Alex Torres on three of his four touchdown passes as Texas Tech ended Oklahoma’s 39-game home winning streak.

The Sooners are now 75-3 at Owen Field in Bob Stoops’ 13 years as Oklahoma coach.

Landry Jones ended up with 412 yards passing and five touchdowns, but it wasn’t enough for Oklahoma to come back from a sluggish start and save its unbeaten season.

In East Lansing, Michigan, Keith Nichol caught a 44-yard desperation heave from Kirk Cousins on the game’s final play to lift Michigan State to a stunning win over Wisconsin.

With 4 seconds left, Cousins rolled out to his right and threw the ball toward the end zone, where it caromed off Michigan State receiver B.J. Cunningham’s facemask back to Nichol. He fought off two Wisconsin defenders to score.

In Boise, Idaho, Kellen Moore threw for 281 yards and three touchdowns and Doug Martin rushed for 125 yards and two scores as Boise State struggled to beat Air Force.

Moore’s victory gave him 45 career wins, putting him in a tie with Colt McCoy for most wins all-time for college quarterbacks.

Boise State got 423 yards total offense, but its defense struggled to stop Air Force’s potent option game. The Falcons pounded out 265 rushing yards, helping them control the clock and keep Boise State’s offense off the field.

In Columbia, Missouri, Joseph Randle scored four touchdowns as Oklahoma State ended Missouri’s 10-game home winning streak.

Randle had 138 yards on 14 carries and scored on runs of 16, 59 and 12 yards. He also caught a 13-yard touchdown pass in the second quarter.

Oklahoma State quarterback Brandon Weeden was 33 for 49 for 338 yards and three touchdowns passes.

In Stanford, California, Stepfan Taylor, Tyler Gaffney and Anthony Wilkerson powered Stanford to a school-record 446 yards rushing.

Taylor ran for 138 yards, Gaffney 117 yards and Wilkerson 93 yards to break the previous team mark of 439 in a victory over Oregon State in 1981. The Cardinal extended the nation’s longest winning streak to 15 games.

Chris Polk ran for scores from 46 and 61 yards in the first half to keep Washington close early.

In Clemson, South Carolina, Tajh Boyd equaled a school record with five touchdown passes as Clemson improved to 8-0 for the first time in 11 years.

Boyd matched Cullen Harper’s 2007 mark as the Tigers gained 450 total yards. Kourtnei Brown scored on interception and fumble returns, becoming the first Clemson defensive lineman to score a pair of touchdowns in one game in 57 years.

At Boulder, Colorado, Oregon trounced Colorado despite playing without injured quarterback Darron Thomas and running back LaMichael James.

With Bryan Bennett under center and Kenjon Barner at tailback, the Ducks used four drives that averaged just 1:36 each to build a 29-0 lead after one quarter. Barner had touchdown runs of 4 and 84 yards and Bennett found running back De’Anthony Thomas for a 14-yard touchdown and tight end David Paulson from 31 yards out.

In Oxford, Mississippi, Tyler Wilson threw for 232 yards and rushed for two touchdowns as Arkansas rallied from an early 17-point deficit.

Dennis Johnson rushed for 160 yards on 15 carries, including a 52-yard touchdown, and Joe Adams caught four passes for 124 yards for Arkansas.

Ole Miss took a surprising 17-0 lead with 6:20 remaining in the second quarter after Randall Mackey’s 3-yard touchdown run, but the Razorbacks responded with 29 unanswered points.

In Manhattan, Kansas, Collin Klein threw for a career-high 195 yards and scored five touchdowns to help Kansas State to its best start since 1999.

Tyler Lockett also returned a kickoff for a score and caught a touchdown pass for the Wildcats, who host the third-ranked Oklahoma Sooners next week in a matchup that should go a long way toward deciding the Big 12 champion.