Lester (5-2) remained unbeaten in his last seven starts, striking out nine and allowing one baserunner past second. Manny Delcarmen, Daniel Bard and Jonathan Papelbon finished the combined one-hitter.

The victory was the seventh in eight games for the Red Sox, who are a season-best five games over .500 (26-21). Papelbon earned his 11th save in 12 opportunities.

The Rays, who have baseball’s best record at 32-14, lost a series at home for the first time since dropping two of three to the New York Yankees the opening week of the season.

Willy Aybar had their lone hit, a fourth-inning single.

James Shields(5-2) limited the Red Sox to four hits over eight innings.

At Baltimore, Ty Wigginton and Adam Jones delivered successive sacrifice flies in the sixth inning for Baltimore.

Jeremy Guthrie (3-4) gave up one run and six hits in six innings for the Orioles, who took a 3-1 lead against Tyson Ross (1-3) without benefit of a hit.

Nick Markakis hit a solo homer in the eighth, and Matt Wieters added an RBI double.

Oakland starter Dallas Braden left after allowing an unearned run and three hits in four innings, throwing only 62 pitches. Braden is winless in three starts since his perfect game against Tampa Bay on May 9.

The defeat ended Oakland’s three-game winning streak.

At Cleveland, Cleveland rookie Mitch Talbot outpitched former NL Cy Young winner Jake Peavy.

Jason Donald and Shin-Soo Choo homered in the Indians’ three-run third inning off Peavy (3-4). The Indians made it 6-0 with a three-run sixth off the right-hander, who won the award in 2007 with San Diego.

Talbot (6-3) allowed two runs and six hits over seven innings to win for the third time in four starts. He took a two-hit shutout into the seventh before giving up four doubles.

Donald hit his first career homer, while Choo hit his seventh of the season. Travis Hafner followed with a ground-rule double and scored on Russell Branyan’stwo-out single to make it 3-0.

Peavy gave up eight hits and six runs over six innings.

At Minneapolis, the first rain delay in Target Field history became the first suspended game. Umpires suspended the game between New York and Minnesota after a 1-hour, 23-minute rain delay with the score 0-0 after five innings.

The game was to resume in the top of the sixth on Wednesday at 4:10 p.m.

The Twins moved outdoors to Target Field this season after 28 years under the protective roof of the Metrodome. The Twins have already had one game postponed — on May 7 against Baltimore. But this was the first time a game was delayed while in progress.

The last outdoor delay in Minnesota was a 48-minute pause at Met Stadium on Sept. 26, 1981 against Texas.

At Kansas City, Missouri, Vladimir Guerrero hit two two-run homers and drove in five runs for Texas.

Guerrero is hitting .444 with five home runs and 12 RBIs against Kansas City this season. It was his 41st multihomer game and second this season, both against the Royals.

Guerrero homered in the first and fifth innings and added an RBI double in the seventh.

Josh Hamilton and Nelson Cruz hit back-to-back homers in the fourth inning off Royals starter Gil Meche, who gave up four home runs in the first five innings after yielding only three in his first eight starts.

The Royals tied it at 6 with a three-run sixth.

Darren O’Day (2-2) allowed one run and three hits in one inning. Rookie Neftali Feliz worked the ninth for his 13th save in 15 opportunities.

Brad Thompson (0-3), the second of five Kansas City pitchers, lost after giving up two runs and two hits without retiring a batter.

At Anaheim, California, Ervin Santana pitched a four-hitter for his second complete game against Toronto this season and Mike Napoli homered for Los Angeles.

Santana (4-3) finished with 10 strikeouts, one off his career high, after getting staked to an early 5-0 lead.

Toronto’s first three hits against the right-hander came on first-pitch homers by Jose Bautista, Aaron Hilland Jeremy Reed.

Bobby Abreu and Erick Aybar each had two RBIs for the Angels.

Ricky Romero(4-2) went 5 1-3 innings, giving up seven runs, 11 hits and three walks.

The Blue Jays, who lead the majors with 78 home runs, did not get their first hit until Bautista’s 15th homer in the fifth.

In Seattle, Milton Bradley homered and then drove in the go-ahead run in the eighth inning with a single off Justin Verlanderto help Seattle rally.

Shawn Kelley (3-0) pitched the eighth before David Aardsma finished for his 10th save in 12 chances. It was his second save of May, as the Mariners improved to 6-16 this month.

Chone Figgins, hitting .195, doubled off Verlander (5-3) with one out in the eighth. Franklin Gutierrez, who had homered in the sixth to tie the game at 3, walked.

Bradley followed with a single.

The only other time Bradley drove in three runs in a game this season was April 13, when his three-run home run beat Oakland. That was his last homer until his two-run shot off Verlander gave Seattle a 2-0 lead in the first inning.

Seattle’s Doug Fister allowed two earned runs and nine hits in seven innings. His AL-leading ERA ticked up to 2.03.