Also beaten were fourth-seeded Agnieszka Radwanska and sixth-seeded Flavia Pennetta. Kim Clijsters fared far better in her first match on grass in nearly four years, defeating fellow Belgian Yanina Wickmayer 6-1, 6-1 in this Wimbledon warmup.

On the men’s side on a blustery day, second-seeded Spaniard Feliciano Lopez retired after receiving shoulder treatment. He was trailing British wild card James Ward 6-3, 5-4.

Schiavone, seeded second, fell to Romania’s Sorana Cirstea 7-5, 6-3. The top-seeded Wozniacki lost 6-4, 1-6, 6-3 to France’s Aravane Rezai.

“She tried to take the ball early and hit every shot,” Wozniacki said. “Definitely, I would like to have got some more matches here but I just need to keep my head up and play some practice matches and prepare for Wimbledon that way.”

Clijsters last played on grass in the 2006 Wimbledon semifinals. On Tuesday, she ousted her 20-year-old opponent in 54 minutes.

“Yanina definitely wasn’t playing her best tennis today,” Clijsters said. “But at the same time from the beginning on I was very aggressive and really trying to go for the lines a lot.”

Radwanska,  the 2008 champion, lost 7-6 (2), 6-1 to Victoria Azarenka of Belarus. Pennetta was beaten 7-6 (5), 6-1 by Russian qualifier Ekaterina Makarova. Nadia Petrova struggled before edging Croatian qualifier Karolina Sprem 2-6, 7-5, 7-6 (4).
 

In Den Bosch, Netherlands, Xavier Malisse of Belgium has reached the quarterfinals of the Unicef Open with a 4-6, 6-1, 7-5 victory over Daniel Brands.

Malisse was within two points of losing Tuesday’s second-round match before rallying to reach the quarterfinals for the second week in a row. He made it to the final eight at the Queen’s Club.

In first-round play, eighth-seeded Benjamin Becker of Germany defeated Jarkko Nieminen of Finland 6-4, 3-6, 6-4.
 

Meantime, Elena Dementieva has pulled out of next week’s Wimbledon because of a calf injury, the Russian world No. 5  said on Tuesday.

“(I) will not play at Wimbledon this year,” she said on her official website (www.dementieva.ru).

The 28-year-old Muscovite suffered the injury during the French Open, forcing her to retire from her semi-final earlier this month against eventual winner Francesca Schiavone.

In Paris, Dementieva said she first suffered the problem to her left calf in a second-round win over Anabel Medina Garrigues.

“It was very painful to even walk. I couldn’t really move on the court,” she said at the time.

The Olympic champion would have been a legitimate title contender at the grass-court major after reaching the semi-finals at the All England Club last year.

She had a match point against Serena Williams before losing 6-7, 7-5, 8-6 to the American, who went on to claim her third Wimbledon crown.

Dementieva, who has yet to win a grand slam title, did not say when she planned to return to the Tour. Initially, she said the injury could take up to six or seven weeks to heal.