Brian Elliott made 34 saves as Alfredsson notched his point milestone with an empty-net goal with 22 seconds left to help the Senators win for the first time in five tries this season on the road.

Ryan Shannon also scored for Ottawa, which came in with an NHL-low three points.

Tim Connolly scored twice for the Sabres.

At Atlanta, Steven Stamkos scored three goals for his second NHL hat trick, and Vincent Lecavalier added a goal and an assist as Tampa Bay downed Atlanta.

Stamkos completed the hat trick with an empty-netter with 32 seconds left, his eighth goal of the season.

Mike Smith made 28 saves to win his fourth straight start for Tampa Bay. Brett Clark also scored for the Lightning.

Jim Slater and Dustin Byfuglien scored for Atlanta.

At Columbus, Ohio, Rene Bourque scored three goals and added an assist, and Henrik Karlsson stopped 20 shots in his NHL debut to lead Calgary past Columbus.

Niklas Hagman, Ian White and Alex Tanguay also scored for the Flames. Jarome Iginla had three assists and Olli Jokinen, Matt Stajan and Robyn Regehr each added two assists.

It was Bourque’s second career hat trick.

Derek Dorsett and Jan Hejda had goals for Columbus, beaten badly for the second time in three home games.

At St. Louis, Roman Polak broke a broke a third-period tie, and David Perron scored twice to help St. Louis avenge an overtime loss in Chicago on Monday.

Patrik Berglund also scored, T.J. Oshie had two assists and Jaroslav Halak stopped 23 shots for the Blues. Patrik Sharp and Brent Seabrook scored for the Blackhawks. Marty Turco stopped 24 shots in the loss that snapped Chicago’s winning streak at four.

At Vancouver, British Columbia, Manny Malhotra had two goals and an assist, and rookie backup Cory Schneider made 23 saves as Vancouver downed Minnesota.

Raffi Torres, Ryan Kesler and Jeff Tambellini also scored, and Jannik Hansen added two assists to help the Canucks avenge a 6-2 loss in Minnesota on Tuesday night.

That was the game that Canucks forward Rick Rypien grabbed a Minnesota fan while being sent to the dressing room after a fight with Brad Staubitz. Rypien was suspended six games by the NHL on Friday.

Antti Miettinen ended Schneider’s bid for his first NHL shutout with 2:35 left, snapping a shot off the goalie’s glove and just over the goal line. Jose Theodore made 30 saves in his Minnesota debut.