It was a new nadir in a lost season for the Cowboys (1-7), who came into 2010 with Super Bowl aspirations. And it’s sure to kick off a new round of speculation about the future of coach Wade Phillips, despite recent statements from team owner Jerry Jones that a midseason firing was unlikely.

James Jones caught eight passes for 123 yards and a touchdown for the Packers (6-3), who have won three straight.

Green Bay’s Clay Matthews added a final dose of embarrassment in the fourth quarter, picking off a pass from Jon Kitna and running it back 62 yards for a touchdown.

Browns 34 Patriots 14: At Cleveland, rookie quarterback Colt McCoy scrambled for a touchdown, and Peyton Hillis ran for a career-high 184 yards and two scores as Cleveland pounded New England.

Two weeks after stunning New Orleans, the Browns (3-5) pulled off another shocker. Well rested after their bye week, they ended New England’s five-game winning streak and did it decisively, outplaying one of the NFL’s top teams for all 60 minutes.

Vikings 27 Cardinals 24 OT: At Minneapolis, Brett Favre rallied Minnesota from 14 points down to tie it with 27 seconds to play, then drove them into position for Ryan Longwell’s 35-yard game-winning field goal.

Favre threw for a career-high 446 yards with two touchdowns and two interceptions for the Vikings (3-5), who fought back cheers of “Fire Childress!” early in the game to pull out the win.

Raiders 23 Chiefs 20 OT: At Oakland, California, Jason Campbell threw a 47-yard pass to rookie Jacoby Ford in overtime to set up a 33-yard field goal by Sebastian Janikowski that gave Oakland its biggest win in eight years.

Campbell and Ford hooked up on a 29-yard pass in the closing seconds of regulation to set up Janikowski’s tying 41-yard field goal. The Raiders (5-4) then won it in overtime for their most significant victory since winning the 2002 American Football Conference championship.

Jets 23 Lions 20 OT: At Detroit, Mark Sanchez threw a 52-yard pass to Santonio Holmes to set up Nick Folk’s game-winning 30-yard field goal 2:18 into overtime.

Sanchez scored on a quarterback sneak with 2:46 left in regulation and led a nine-play drive that set up Folk’s 36-yard kick to send the game into OT.

Matthew Stafford threw two touchdown passes and ran for a score to give Detroit a 10-point lead before re-injuring his right shoulder and leaving the game with 5:19 left.

Eagles 26 Colts 24: At Philadelphia, Michael Vick threw for 218 yards and one touchdown, ran for 74 yards and a score, as Philadelphia beat Peyton Manning and Indiana.

The Eagles (5-3) are 12-0 after a bye since Andy Reid became coach in 1999. They hadn’t beaten Manning in three previous tries.

Saints 34 Panthers 3: At Charlotte, North Carolina, Drew Brees threw for 253 yards and two touchdowns, Jabari Greer returned an interception for a touchdown and New Orleans became the latest team to shut down Carolina’s NFL-worst offense.

The Saints (6-3) overcame the loss of tight end Jeremy Shockey to a rib injury after his touchdown catch to keep pace in the competitive NFC South. Rookie tight end Jimmy Graham caught his first NFL TD in Shockey’s absence and the Saints held Carolina to 195 yards.

Giants 41 Seahawks 7: At Seattle, Eli Manning threw for three first-half touchdowns, and Ahmad Bradshaw added a pair of rushing touchdowns as the Giants downed Seattle.

Manning and the Giants (6-2) jumped to a 35-0 halftime lead, overwhelming the banged up Seahawks and staking claim as maybe the best team in the NFC halfway through the season.

Bears 22 Bills 19: At Toronto, Jay Cutler threw two touchdown passes, including one to Earl Bennett late in the fourth quarter, to give Chicago a win and keep Buffalo winless.

Chester Taylor also scored on a 1-yard plunge for the Bears (5-3), who came out of their off week to end a two-game skid. Tim Jennings’ interception came early in the fourth quarter, and with Chicago trailing 19-14.

Falcons 27 Buccaneers 21: At Atlanta, Michael Turner scored two early touchdowns and Atlanta held off Tampa Bay with a gutty goal-line stand to take over sole possession of first place in the NFC South.

Turner rushed 24 times for 107 yards, including scoring plays of 2 and 10 yards that gave the Falcons (6-2) an early 14-0 lead. Atlanta was hanging on at the end against the Buccaneers (5-3), whose coach, Raheem Morris, had proclaimed his team the best in the NFC.

Chargers 29 Texans 23: At Houston, Philip Rivers threw four touchdown passes against the NFL’s worst pass defense as San Diego earned its first road win of the season.

Rivers completed 17 of 23 passes for 295 yards. He used eight different receivers in the absence of tight end Antonio Gates, who was out with a right foot injury.

Ravens 26 Dolphins 10: At Baltimore, Billy Cundiff made four field goals as Baltimore cranked up the defense after halftime to hand Miami its first road loss.

Baltimore (6-2) won its seventh straight at home behind Cundiff and a defense that blanked Miami (4-4) in the second half. Cundiff connected from 26, 39, 20, 24 yards, and the Ravens held the Dolphins to 24 yards rushing over the final 30 minutes.

Dolphins quarterback Chad Henne went 22 for 34 for 231 yards and three interceptions.