Vick started despite suffering a concussion in last week’s 35-31 loss at Atlanta. He left with a broken right hand in the fourth quarter after helping the Eagles overcome a 14-0 first-quarter deficit to take a 16-14 lead.

It’s uncertain how long Vick will be out.

Without their Pro Bowl quarterback, the Eagles (1-2) hardly look like the “Dream Team” that entered the season with Super Bowl or bust expectations.

Elsewhere, Baltimore routed Sam Bradford and the St. Louis Rams 37-7, and Matt Ryan’s Atlanta Falcons fell to Tampa Bay 16-13.

Also, it was Green Bay 27, Chicago 17; Buffalo 34, New England 31; New Orleans 40, Houston 33; Detroit 26, Minnesota 23 in overtime; Pittsburgh 23, Indianapolis 20; Tennessee 17, Denver 14; Carolina 16, Jacksonville 10; San Diego 20, Kansas City 17; Seattle 13, Arizona 10; Cleveland 17, Miami 16; and San Francisco 13, Cincinnati 8.

At Orchard Park, New York, Rian Lindell hit a 28-yard field goal as time expired as Buffalo snapped a 15-game losing streak against New England and lifted its record to 3-0.

Buffalo was in dramatic fashion, overcoming a 21-0 second-quarter deficit. It’s the second straight week the Bills rallied; they overcame a 21-3 deficit in a 38-35 win over Oakland last week.

Ryan Fitzpatrick went 27 of 40 for 369 yards with two TDs as Buffalo beat its AFC East rival for the first time since the 2003 opener.  

At Minneapolis, Matthew Stafford threw for 378 yards and two touchdowns to rally Detroit Lions from a 20-0 halftime deficit, and Jason Hanson kicked a 32-yard field goal in overtime.

Calvin Johnson had seven catches for 108 yards and two TDs for the Lions — 3-0 for the first time since 1980. 

At Chicago, Aaron Rodgers threw for 297 yards and three touchdowns to Jermichael Finley , as Green Bay shut down Jay Cutler.

The stakes weren’t as high as the previous meeting, when the Packers left Soldier Field celebrating the NFC title on the way to the championship. 

At Tampa, Florida, Josh Freeman scored the first rushing touchdown of his career and Tampa Bay’s defense forced three turnovers and sacked Matt Ryan four times.

The normally unflappable Freeman did a little bird dance in celebration of his quarterback sneak that snapped a 3-3 tie in the second quarter, and the Bucs (2-1) went on to end a five-game losing streak in the series between NFC South rivals.

At New Orleans, Drew Brees passed for 370 yards and three touchdowns, and twice led New Orleans back from fourth-quarter deficits.

Mark Ingram’s first career touchdown on a 13-yard run gave the Saints (2-1) the lead for good with under 3 minutes left.

At Charlotte, North Carolina, Cam Newton didn’t pass for too many of yards, he simply found Greg Olsen over the middle for a 16-yard touchdown with 4:20 left to list Carolina (1-2).

Newton, the No. 1 overall draft pick, also found Olsen for the ensuing 2-point conversion that helped Carolina rally from a 10-5 halftime deficit. 

At Nashville, Tennessee, Matt Hasselbeck threw a 4-yard touchdown pass to Daniel Graham with 4:24 left to completed Tennessee’s rally.

The Titans (2-1) lost Kenny Britt , the AFC’s leading receiver, when his right knee buckled in the second quarter.

At Oakland, California, Darren McFadden ran for 171 yards and two touchdowns as Oakland bullied the two-time defending AFC runners-up on the ground to win their home opener.

Denarius Moore scored on a 23-yard reverse and Michael Bush added a 1-yard TD run 42 seconds later as the Raiders (2-1) took control in a dizzying span beginning late in the third quarter to hand the Jets (2-1) their first loss.

At San Diego, Eric Weddle intercepted Matt Cassel at midfield with 55 seconds left to preserve San Diego’s victory over winless Kansas City.

The Chiefs (0-3) got the ball back at its 33 with 1:26 left after Philip Rivers was stuffed on fourth-and-1 at the Chiefs 34.

At Indianapolis, Shaun Suisham kicked a 38-yard field goal with 4 seconds left to lift Pittsburgh over Indianapolis.

It was a wild game that turned three times in the final 5 1/2 minutes and was far closer than most expected.

The Steelers (2-1) struggled as Ben Roethlisberger lost two fumbles and threw an interception during an 11-minute first-half span, and they rushed for only 67 yards.

At St. Louis, rookie Torrey Smith’s first three career catches went for touchdowns totaling 133 yards in the first quarter, sparking a franchise record-setting day on offense by Baltimore.

The Ravens (2-1) got back on their game and then some after stumbling in a loss at Tennessee last week. The 406-yard first half that fueled a 27-point cushion, and the game total of 553 yards, were both bests for the franchise that moved from Cleveland in 1996.

At Cleveland, Colt McCoy threw a 14-yard touchdown pass to Mohamed Massaquoi with 43 seconds left to cap an 80-yard drive and rally Cleveland (2-1) over winless Miami.

The loss surely will bring more heat on embattled Dolphins coach Tony Sparano.

At Cincinnati, Kendall Hunter ran 7 yards for the game’s only touchdown with 3:59 to go, rallying San Francisco in front of Cincinnati’s smallest crowd for a home opener in 30 years.

Hunter’s run completed the only noteworthy drive by the 49ers (2-1), who didn’t cross midfield until midway through the third quarter.

At Seattle, Tarvaris Jackson scrambled for an 11-yard touchdown run early in the third quarter, bulling through two Arizona defenders at the goal line, and Seattle (1-2) picked up its first win.

Jackson’s day had a little bit of everything, from fans booing, to later chants for his backup Charlie Whitehurst