LOUISVILLE, Kentucky: Teddy Bridgewater threw five touchdown passes and Michael Dyer had a 46-yard touchdown run as No. 9 Louisville defeated Ohio 49-7 on Sunday.

Coming off an 11-2 finish and a Sugar Bowl upset of Florida, Bridgewater and the Cardinals (1-0) dominated. That pleased a sellout crowd of 55,332 seeing them for the first time since that BCS win set off the school’s remarkable run of success that included an NCAA men’s basketball title, the women’s team’s runner-up NCAA finish and an appearance in College World Series.

Bridgewater kicked off his Heisman Trophy campaign by going 23 of 28 for 355 yards. Damian Copeland and Kai De La Cruz each caught two touchdowns and DeVante Parker and Robert Clark each had one.

Dyer, the former Auburn star, debuted for Louisville and the Cardinals outgained Ohio 615-273.

Colorado 41 Colorado State 27: At Denver, Greg Henderson scored on a 53-yard fumble return in the fourth quarter and Connor Wood threw three touchdown passes — two to speedster Paul Richardson — to help Colorado in Mike MacIntyre’s coaching debut for the Buffaloes.

Richardson was back on the field after missing last season because of a torn left ACL.

FCS full of upsets

The labels on North Dakota State and Eastern Washington say FCS for Football Championship Subdivision, Division I’s second tier. The reality is there are 123 programs and the range of quality is as great as the difference between the best teams in the Football Bowl Subdivision (aka tier 1) and the worst.

The FCS won eight games against FBS opponents during the opening weekend of college football. The most notable victories were by two-time defending FCS champion North Dakota State, which beat Kansas State on Friday night, and Eastern Washington, which knocked off No. 25 Oregon State on Saturday.