Third-seeded John Isner faced his friend and doubles partner James Blake in the late match at the Racquet Club of the South.

Anderson credited his improving play near the net with helping him beat Michael Russell 6-1, 7-5. Muller used 15 aces to defeat local favorite Robby Ginepri 7-6 (6), 2-6, 6-2.

Lu held off qualifier Marinko Matosevic of Australia 3-6, 6-1, 6-2.