The bases were loaded when Altuve hit a hard grounder to Brandon Phillips, who grabbed it and made a throw home from his knees. But catcher Ryan Hanigan couldn’t handle the throw, allowing Humberto Quintero to score.

Quintero singled with no outs in the 10th inning before pinch-hitter Angel Sanchez singled to shallow center field to send Quintero to third base. Logan Ondrusek (4-4) then intentionally walked Brian Bogusevic to load the bases and bring up Altuve.

The Astros debuted a retooled lineup that featured several new faces after they traded stars Hunter Pence and Michael Bourn this weekend and sent former starters Chris Johnson and Brett Wallace to Triple-A.