Rescue crews freed the woman who was trapped in the wreckage in a rural area about a mile (1.6 kilometers) east of the Lebanon-Lancaster exit, turnpike spokesman Carl DeFebo said. Twenty-nine people, including the driver, were aboard, said Greyhound spokesman Maureen Richmond, though a turnpike spokesman said he had information that the total might be 25 because of possible duplicates on the driver’s manifest.

Officials at three hospitals said 14 people altogether were brought in. Four uninjured passengers were picked up by another bus; the conditions of the others were unclear.

The bus from New York City stopped in Philadelphia and had traveled about 75 miles (120 kilometers) westbound on the turnpike when it overturned at about 6 a.m. on the way to a stop in Columbus, Ohio.

State police said the driver lost control of the bus while traveling in the passing lane.

The front end of the bus struck a concrete barrier and the left rear side rode up against the barrier, according to state police. The bus then crossed over the travel lanes, struck an embankment and traveled up the embankment before flipping over on its left side.

Both westbound lanes of the turnpike were closed until about 10:20 a.m., forcing drivers to be rerouted off the interstate. Traffic backed up for about three miles (five kilometers) while crews worked to upright the bus, DeFebo said.

The injured were taken to hospitals in Hershey, Lancaster and Lebanon, according to officials at the hospitals.

At least 12 were being treated and released. Hershey Medical Center admitted one victim, who was listed in fair condition at late morning, and said the other victim might be admitted. At Lancaster General Hospital, staff were evaluating five patients, said nursing supervisor Jan Frailey.

The crash is the latest in a series of tour bus accidents in the Northeast this year, though most of those involved smaller operators.

More than 30 people have been killed and more than 300 injured in tour bus accidents this year, according to Advocates for Highway and Auto Safety. That’s more than in all of last year, when there 30 killed and 272 injured in 28 crashes.

Tour bus industry safety has drawn heightened attention since the March crash of a bus returning to New York City’s Chinatown after an overnight excursion to a Connecticut casino. Fifteen people were killed when the bus flipped onto its side and struck a pole, peeling off its roof.