Oxford University to test potential COVID-19 ‘wonder drug’ Ivermectin

The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives. (Shutterstock/File Photo)
The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives. (Shutterstock/File Photo)
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Updated 23 January 2021

Oxford University to test potential COVID-19 ‘wonder drug’ Ivermectin

The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives. (Shutterstock/File Photo)
  • Medicine used for parasitic worm infections
  • Other scientists said the drug had not been assessed properly

LONDON: Oxford University researchers are planning to trial a drug that has shown signs of reducing COVID-19 deaths in developing countries.

The Principle trial is aiming to find a drug that works soon after virus symptoms appear in a patient, and one that is most effective during the primary stages of the illness, The Times reported.

The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives, the report added.

Other scientists said the drug had not been assessed properly and that the full extent of its efficacy was not yet known.

“It has potential antiviral properties and anti-inflammatory properties and there have been quite a few smaller trials conducted in low and middle- income countries, showing that it speeds recovery, reduces inflammation and reduces hospitalisation,” said Chris Butler, professor of primary care at Oxford and co-chief of the Principle trial. “But there’s a gap in the data. There’s not been a really rigorous trial.”

The medicine works by blocking the entry of a protein into a cell’s nuclei, limiting the replication capacity of the virus, and initial analysis from the World Health Organization has shown promising signs.

“It could save thousands of lives a day,” said Paul Marik, from the Eastern Virginia Medical School. “The data is compelling: across Mexico, India and South America, mortality has fallen.”

Peter Horby, the Oxford University professor who helped to set up the UK’s largest COVID-19 trials, said this month the latest data was “interesting, perhaps encouraging, but not yet convincing.”

Most breakthroughs in coronavirus treatments to date work on patients who are already suffering in the later stages of the illness, but Butler and his team are hoping to find a medicine that can prevent the virus from taking hold within its host.

The trial is looking for people aged 65 and over, or those aged over 50 who have underlying health conditions, through general practitioners, online, and through the UK’s NHS Test and Trace system, The Times said.


27 still missing after Indonesia volcanic eruption kills 15

27 still missing after Indonesia volcanic eruption kills 15
Updated 4 sec ago

27 still missing after Indonesia volcanic eruption kills 15

27 still missing after Indonesia volcanic eruption kills 15
  • Mount Semeru spewed thick columns of ash as high as 12,000 meters into the sky in a sudden eruption triggered by heavy rain
SUMBERWULUH, Indonesia: Rescuers dug out the body of 13-year-old boy with their bare hands on Monday, as improved weather conditions allowed them to resume their search after the highest volcano on Indonesia’s Java island erupted with fury, killing at least 15 people with searing gas and ash and leaving 27 others missing.
Mount Semeru in Lumajang district in East Java province spewed thick columns of ash as high as 12,000 meters into the sky in a sudden eruption Saturday triggered by heavy rain. Villages and nearby towns were blanketed by tons of volcanic debris.
Searing gas raced down the sides of the mountain, smothering entire villages and killing or seriously burning those caught in its path.
National Disaster Mitigation Agency spokesperson Abdul Muhari said 56 people had been hospitalized, mostly with burns. He said rescuers were still searching for 27 villagers reported missing. Nearly 3,000 houses and 38 schools were damaged, Muhari said.
The body of the 13-year-old boy was recovered in the worst-hit village of Sumberwuluh, where houses were buried to their rooftops and cars were submerged. Crumpled roofs, charred carcasses of cattle and broken chairs covered in gray ash and soot dotted the smoldering landscape.
Search and rescue efforts were temporarily suspended Sunday afternoon because of fears that heavy rain would cause more hot ash and debris to fall from the crater.
The eruption of the 3,676-meter-high mountain eased pressure that had been building under a lava dome in the crater. But experts warned that the dome could further collapse, causing an avalanche of blistering gas and debris trapped beneath it.
More than 1,700 villagers escaped to makeshift emergency shelters after Saturday’s powerful eruption, but many others defied official warnings and chose to remain in their homes to tend their livestock and protect their property.
Semeru, also known as Mahameru, has erupted many times in the last 200 years. Still, as on many of the 129 volcanoes monitored in Indonesia, tens of thousands of people live on its fertile slopes. It last erupted in January, with no casualties.
Indonesia, an archipelago of more than 270 million people, is prone to earthquakes and volcanic activity because it sits along the Pacific “Ring of Fire,” a horseshoe-shaped series of fault lines.

Next pandemic could be more lethal than COVID-19, Oxford vaccine creator says

Next pandemic could be more lethal than COVID-19, Oxford vaccine creator says
Updated 40 min 34 sec ago

Next pandemic could be more lethal than COVID-19, Oxford vaccine creator says

Next pandemic could be more lethal than COVID-19, Oxford vaccine creator says

LONDON: Future pandemics could be even more lethal than COVID-19 so the lessons learned from the pandemic must not be squandered, one of the creators of the Oxford-AstraZeneca vaccine said.
“This will not be the last time a virus threatens our lives and our livelihoods,” Sarah Gilbert said in the Richard Dimbleby Lecture, the BBC reported. “The truth is, the next one could be worse. It could be more contagious, or more lethal, or both.”
“We cannot allow a situation where we have gone through all we have gone through, and then find that the enormous economic losses we have sustained mean that there is still no funding for pandemic preparedness,” she said. “The advances we have made, and the knowledge we have gained, must not be lost.”


Myanmar’s Aung San Suu Kyi jailed for four years: Junta spokesman

Myanmar’s Aung San Suu Kyi jailed for four years: Junta spokesman
Updated 06 December 2021

Myanmar’s Aung San Suu Kyi jailed for four years: Junta spokesman

Myanmar’s Aung San Suu Kyi jailed for four years: Junta spokesman
  • For inciting dissent against the military and breaching COVID-19 rules
  • Former president Win Myint was also jailed for four years under the same charges

YANGON: A Myanmar court on Monday jailed ousted civilian leader Aung San Suu Kyi for four years for inciting dissent against the military and breaching COVID-19 rules, a spokesman for the ruling junta SAID.
Suu Kyi “was sentenced to two years’ imprisonment under section 505(b) and two years’ imprisonment under natural disaster law,” junta spokesman Zaw Min Tun said.
Former president Win Myint was also jailed for four years under the same charges, he said, adding that they would not yet be taken to prison.
“They will face other charges from the places where they are staying now” in the capital Naypyidaw, he added, without giving further details.
The 76-year-old Suu Kyi has been detained since the generals ousted her government in the early hours of February 1, ending Myanmar’s brief democratic interlude.
The junta has since added a slew of other indictments, including violating the official secrets act, corruption and electoral fraud. The Nobel laureate faces decades in jail if convicted on all counts.
Journalists have been barred from proceedings in the special court in the military-built capital, and Suu Kyi’s lawyers were recently banned from speaking to the media.
More than 1,300 people have been killed and over 10,000 arrested in a crackdown on dissent since the coup, according to a local monitoring group.


Norwegian Cruise ship detects one probable case of omicron variant

Norwegian Cruise ship detects one probable case of omicron variant
Updated 06 December 2021

Norwegian Cruise ship detects one probable case of omicron variant

Norwegian Cruise ship detects one probable case of omicron variant
  • The probable case was found among 10 people who tested positive for the virus on Saturday

A probable case of the omicron variant has been identified in a crew member of a Norwegian Cruise ship that reached New Orleans on Sunday after detecting COVID-19 among some crew and guests, the Louisiana Department of Health said.
The probable case was found among 10 people who tested positive for the virus on Saturday, the health agency said in a tweet on Sunday.
Another seven cases have since been reported, it added, taking the total number of cases among passengers and crew of Norwegian Breakaway, a cruise ship owned by Norwegian Cruise Line Holdings Ltd. , to 17.
“At this time, there have been no changes to scheduled future sailings on Norwegian Breakaway,” a spokesperson for Norwegian Cruise Line said in a statement to Reuters.
The cruise ship departed New Orleans on a week-long cruise on Nov. 28 and had stops in Belize, Honduras and Mexico, the health agency said.
“NCL has been adhering to appropriate quarantine and isolation protocols,” the department said in an earlier tweet.


Gambian President Barrow wins re-election; opposition cries foul

Gambia's president-elect Adama Barrow waves to his supporters after he gives a victory speech in Banjul, Gambia December 5, 2021. Picture taken December 5, 2021. (REUTERS)
Gambia's president-elect Adama Barrow waves to his supporters after he gives a victory speech in Banjul, Gambia December 5, 2021. Picture taken December 5, 2021. (REUTERS)
Updated 06 December 2021

Gambian President Barrow wins re-election; opposition cries foul

Gambia's president-elect Adama Barrow waves to his supporters after he gives a victory speech in Banjul, Gambia December 5, 2021. Picture taken December 5, 2021. (REUTERS)

BANJUL: Gambian President Adama Barrow has comfortably won re-election, the electoral commission said on Sunday, though he may face a legal challenge from opposition candidates who rejected the results because of unspecified irregularities.
The vote was the first in 27 years without disgraced former President Yahya Jammeh, who was forced into exile in Equatorial Guinea after refusing to accept defeat to Barrow in 2016.
Jammeh’s despotic 22-year rule over the small West African nation of 2.5 million people, which began with a 1994 coup, was characterised by killings and torture of political opponents.
Saturday’s peaceful election was seen by many as a victory for democracy that helped draw a line under that troublesome period.
Once cowed by Jammeh’s omnipresent secret police, crowds of people hit the streets of Banjul on Sunday night to celebrate, or drove around in their cars, honking horns. Hundreds gathered in a park opposite the presidential palace to listen to Barrow speak.
“Democracy has taken its course,” Barrow told the cheering crowd after the results were announced. “I have been the lucky person to be chosen by you. I’ll use all the resources to make Gambia a better place for all.”
Barrow’s first term provided a welcome change for many to Jammeh’s brutal tenure. But progress was hobbled by the coronavirus pandemic, which damaged an economy that relies heavily on tourism, as well as exports of peanuts and fish.
In the run-up to the election, Jammeh had tried to persuade supporters to vote for an opposition coalition in telephoned speeches that were relayed to campaign rallies.
But he failed to dent Barrow’s following. The president received around 53 percent of Saturday’s vote, far outstripping his nearest rival, political veteran Ousainou Darboe, who won about 28 percent.
As results came in on Sunday, representatives from all opposition parties signed off on nearly all the tally sheets read to the election commission.
But later in the day, Darboe and two other candidates, Mama Kandeh and Essa Mbye Faal, said they would not accept the results because the results took longer than expected and because of problems at polling stations.
They did not provide specifics or evidence of wrongdoing.
“We are concerned that there had been an inordinate delay in the announcement of results,” their statement said. “A number of issues have been raised by our party agents and representatives at the polling stations.”
The statement did not say what they would do now, only stating that “all actions are on the table.”