WHO wants vaccine efficacy data in monkeypox fight

WHO wants vaccine efficacy data in monkeypox fight
Experts have detected a surge of monkeypox cases since May, most of which have been in western Europe. (Reuters)
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Updated 30 June 2022

WHO wants vaccine efficacy data in monkeypox fight

WHO wants vaccine efficacy data in monkeypox fight
  • The UN health agency decided that monkeypox did not meet the threshold of a so-called Public Health Emergency of International Concern

GENEVA: The World Health Organization on Wednesday appealed for vigilance to ensure monkeypox does not spread among more vulnerable groups, such as children.
Fighting the virus requires “intense” efforts, said the WHO, calling for broad data collection and sharing on how well vaccines work against the virus.
Experts have detected a surge of monkeypox cases since early May outside of the West and Central African countries where the disease has long been endemic. Most of the new cases have been in western Europe.
“I am concerned about sustained transmission because it would suggest that the virus is establishing itself and it could move into high-risk groups including children, the immunocompromised and pregnant women,” WHO chief Tedros Adhanom Ghebreyesus told reporters.
“We are starting to see this, with several children already infected.”
There are two cases aged under 18 in Britain.

WHO chief scientist Soumya Swaminathan called for “very careful studies of the vaccine in different population groups... so that we get data that’s broadly applicable, and also to ensure that children, pregnant women and the immunosuppressed are considered for inclusion in these trials.”
As of June 22 this year, 3,413 laboratory-confirmed monkeypox cases and one death have been reported to the WHO, from 50 countries.
The countries with three-figure case numbers are Britain (793), Germany (521), Spain (520), Portugal (317), France (277), Canada (210), the Netherlands (167) and the United States (142).
The vast majority of cases so far have been observed in men who have sex with men, of young age, chiefly in urban areas, in “clustered social and sexual networks,” according to the WHO.
Last week the UN health agency convened an emergency committee of experts to decide if monkeypox constitutes a so-called Public Health Emergency of International Concern (PHEIC), the highest alarm that the WHO can sound.
But a majority found the situation had not yet crossed that threshold.
Nonetheless, “they acknowledged the emergency nature of the event and that controlling the further spread requires intense response efforts,” Tedros said.

The WHO chief called for equitable access to counter-measures like vaccines and antivirals and the systematic collection of clinical data to inform future recommendations.
WHO emergencies director Michael Ryan said that countries with stockpiles of vaccines, led by the United States, had shown willingness to share them.
However, the vaccines have largely only been licensed for use against monkeypox’s far more severe relative smallpox, which is also caused by an orthopoxvirus and which is the only disease successfully eradicated through vaccination.
“It’s really important as we encourage the sharing of these products that we also collect the necessary clinical efficacy data,” said Ryan.He said the chief intervention in controlling monkeypox should be reducing transmission through education and taking steps to avoid infection, and then targeted use of available vaccines and antivirals.
Currently, vaccines are in short supply and are broadly limited to health workers exposed to higher risk while tracing contacts of cases, said Ryan.
He said some countries were beginning to consider offering vaccines to individuals “engaged in high-risk activities or at particular risk of being exposed.”


WHO urges caution after dog catches monkeypox

WHO urges caution after dog catches monkeypox
Updated 6 sec ago

WHO urges caution after dog catches monkeypox

WHO urges caution after dog catches monkeypox
GENEVA: The World Health Organization called Wednesday for people infected with monkeypox to avoid exposing animals to the virus following a first reported case of human-to-dog transmission.
A first case of human-to-dog transmission of monkeypox — between two men and their Italian greyhound living together in Paris — was reported last week in the medical journal The Lancet.
“This is the first case reported of human-to-animal transmission... and we believe it is the first instance of a canine being infected,” Rosamund Lewis, the WHO’s technical lead for monkeypox, told reporters.
Experts, she said, had been aware of the theoretical risk that such a jump could happen, and that public health agencies had already been advising those suffering from the disease to “isolate from their pets.”
In addition, she said “waste management is critical” to lower the risk of contaminating rodents and other animals outside the household.
It was vital, she said, for people to “have information on how to protect their pets, as well as how to manage their waste so that animals in general are not exposed to the monkeypox virus.”
When viruses jump the species barrier it often sparks concern that they could mutate in a more dangerous direction.
Lewis stressed that so far there was no reports that was happening with monkeypox.
But, she acknowledged, “certainly as soon as the virus moves into a different setting in a different population, there is obviously a possibility that it will develop differently and mutate differently.”
The main concern revolves around animals outside of the household.
“The more dangerous situation... is where a virus can move into a small mammal population with high density of animals,” WHO emergencies director Michael Ryan told reporters.
“It is through the process of one animal infecting the next and the next and the next that you see rapid evolution of the virus.”
He stressed though that there was little cause for concern around household pets.
“I don’t expect the virus to evolve any more quickly in one single dog than in one single human,” he said, adding that while “we need to remain vigilant... pets are not a risk.”
Monkeypox received its name because the virus was originally identified in monkeys kept for research in Denmark in 1958, but the disease is found in a number of animals, and most frequently in rodents.
The disease was first discovered in humans in 1970 in the Democratic Republic of Congo, with the spread since then mainly limited to certain West and Central African countries.
But in May, cases of the disease, which causes fever, muscular aches and large boil-like skin lesions, began spreading rapidly around the world, mainly among men who have sex with men.
Worldwide, more than 35,000 cases have been confirmed since the start of the year in 92 countries, and 12 people have died, according to the WHO, which has designated the outbreak a global health emergency.

Russia replaces Black Sea fleet chief after Crimea setbacks

Russia replaces Black Sea fleet chief after Crimea setbacks
Updated 43 min 28 sec ago

Russia replaces Black Sea fleet chief after Crimea setbacks

Russia replaces Black Sea fleet chief after Crimea setbacks
  • Moscow blamed saboteurs for blasts that engulfed an ammunition depot in northern Crimea on Tuesday
  • Ukraine has not officially taken responsibility but has hinted at it

KYIV/LONDON: Russia has replaced the commander of its Crimea-based Black Sea Fleet, a state news agency reported on Wednesday.
This comes after a series of explosions rocked the peninsula it annexed in 2014 and had previously seen as a secure rear base for its war in Ukraine.
Moscow blamed saboteurs for blasts that engulfed an ammunition depot in northern Crimea on Tuesday. Plumes of smoke were later seen rising at a second Russian military base in central Crimea, Russia’s Kommersant newspaper said.
Ukraine has not officially taken responsibility but has hinted at it. The apparent Ukrainian capability to strike deeper into Russian-occupied territory, either with some form of weapon or with sabotage, indicates a shift in the conflict. Blasts destroyed warplanes at a Russian naval air base in Crimea last week.
On Wednesday, Russia’s RIA news agency cited sources as saying the commander of its Black Sea fleet, Igor Osipov, had been replaced with a new chief, Viktor Sokolov.
If confirmed, the move would mark one of the most prominent sackings of a military official so far in a war in which Russia has suffered heavy losses in men and equipment.
State-owned RIA cited the sources as saying the new chief was introduced to members of the fleet’s military council in the Crimean port of Sevastopol.
The Black Sea Fleet, which has a revered history in Russia, has suffered several humiliations since President Vladimir Putin launched the invasion of Ukraine — which Moscow terms a “special military operation” — on Feb. 24.
In April, Ukraine struck its flagship, the Moskva, a huge cruiser, with Neptune missiles. It became the biggest warship to be sunk in combat for 40 years.

CRUCIAL SUPPLY ROUTE
Crimea, which Russia seized from Ukraine in 2014 and has extensively fortified since then, provides the main supply route for Russian forces in southern Ukraine, where Kyiv is planning a counter-offensive in coming weeks.
Ukrainian military intelligence said in a statement that after the recent explosions in Crimea, Russian forces had urgently moved there some of their planes and helicopters deeper into the peninsula and to airfields inside Russia. Reuters could not independently verify the information.
President Volodymyr Zelensky urged Ukrainians to steer clear of Russian military bases and ammunition stores and said the explosions could have various causes, including incompetence.
“But they all mean the same thing — the destruction of the occupiers’ logistics, their ammunition, military and other equipment, and command posts, saves the lives of our people,” he said in an evening address on Tuesday.
On Wednesday Russia’s FSB security service said it had detained six members of what it called an Islamist terrorist cell in Crimea, though it did not say if they were suspected of involvement in the explosions.
The Black Sea fleet has also blockaded Ukraine’s ports since the start of the war, trapping vital grain exports, which are only now starting to move again under an agreement brokered by Turkey and the United Nations.
Another three ships left Ukraine on Wednesday, the infrastructure ministry said on its Facebook page.
“This morning, three ships with Ukrainian food products left the ports of Chornomorsk and Odesa... More than 33,000 tons of agricultural products are on board,” it said.

’WHERE SHOULD WE GO’
The war has caused millions to flee, killed thousands and deepened a geopolitical rift between the West and Russia, which says the aim of its operation is to demilitarise its neighbor and protect Russian-speaking communities.
Ukraine, which broke free of Moscow’s rule when the Soviet Union broke up in 1991, accuses Russia of waging an imperial-style war of conquest.
Pavlo Kyrylenko, the governor of the eastern Donetsk region, which has seen some of the fiercest fighting, said early on Wednesday that two civilians were killed and seven wounded in shelling by Russian forces in the past 24 hours.
The Ukrainian government has ordered mass evacuations in Donetsk, but for one couple on a small farm near the city of Kramatorsk leaving was not an option.
“Grandmother cannot be transported – she is almost 100 years old,” Nataliia Ataiantz, 47, said as she checked on the elderly woman. For her husband, Oleksandr, the idea of leaving was “scary.”
“Our parents are buried here. And this is our land too ... where should we go, to foreign country?” he said.


Germans spot ‘Russian forces’ in Mali after French exit

Germans spot ‘Russian forces’ in Mali after French exit
Updated 17 August 2022

Germans spot ‘Russian forces’ in Mali after French exit

Germans spot ‘Russian forces’ in Mali after French exit
  • German ambassador in Bamako has contacted Mali’s foreign minister about ‘the suspected presence of Russian uniformed forces in Gao’
  • France announced in February that it was withdrawing its troops from Mali after a breakdown in relations with the country’s ruling junta

BERLIN: German soldiers in Mali spotted several dozen suspected Russian security forces in the city of Gao just as the last French soldiers left the country, the German government said Wednesday.
The German ambassador in Bamako has contacted Mali’s foreign minister about “the suspected presence of Russian uniformed forces in Gao,” said a foreign ministry spokesman.
Gao is home to a contingent of German soldiers, not far from the former base occupied by the French.
A Russian presence in the city would be a development “that changes the mission environment,” the spokesman said, adding that the government was also discussing the matter with the United Nations.
France announced in February that it was withdrawing its troops from Mali after a breakdown in relations with the country’s ruling junta. That ended a near 10-year deployment against extremist groups that pose a growing threat in West Africa.
The arrival of Russian paramilitaries in the country on the invitation of the government was a key factor in France’s decision to pull its military forces out.
The last French soldiers left Mali on Monday.
Germany’s government was also aware of an aircraft being used by Malian armed forces that “could possibly be an aircraft that was handed over by Russia,” said a defense ministry spokeswoman.
“We have received information that about 20 to 30 persons who were not associated with the Malian armed forces were seen loading and unloading this aircraft in a hangar” on Monday, the spokeswoman said.
The government is “intensively investigating” these reports, which concern a “training and ground combat aircraft of the L-39 type,” she said.
Germany on Friday said it had stopped reconnaissance operations and helicopter transport flights in Mali until further notice after Bamako denied flyover rights to the UN peacekeeping mission in Mali, MINUSMA.
But MINUSMA resumed contingent rotations from Monday under new approval procedures.
MINUSMA — the United Nations Multidimensional Integrated Stabilization Mission in Mali — was launched in 2013 to help one of the world’s poorest countries cope with a bloody extremist campaign.
It is one of the UN’s biggest peacekeeping operations, with 17,609 troops, police, civilians and volunteers deployed as of April, according to the mission’s website.


First drought, now downpours as storms slam France, England

First drought, now downpours as storms slam France, England
Updated 17 August 2022

First drought, now downpours as storms slam France, England

First drought, now downpours as storms slam France, England
  • Winds over 100 kph (60 mph) were recorded at the top of the Eiffel Tower during a flash flood Tuesday
  • In southern France, thunderstorms overnight and Wednesday flooded the Old Port of Marseille

PARIS: After a summer of drought, heat waves and forest fires, violent storms are whipping France and have flooded Paris subway stations, snarled traffic and disrupted the president’s agenda.
Winds over 100 kph (60 mph) were recorded at the top of the Eiffel Tower during a flash flood Tuesday, and similar winds were forecast Wednesday in the southeast.
Hail hammered Paris and other regions in Tuesday’s sudden storm. Rainwater gushed down metro station stairwells and onto platforms, and cars sloshed along embankments where the Seine River broke its banks.
In southern France, thunderstorms overnight and Wednesday flooded the Old Port of Marseille and the city’s main courthouse and forced the closure of nearby beaches.
Thunderstorms also appeared in southern England on Wednesday, drenching London tourists and residents after a summer of unusually warm and sunny weather.
The national weather service issued storm warnings for Wednesday and Thursday, advising people to stay alert for possible flooding and power outages.
As scattered storms swept across Belgium on Wednesday, one flooded parts of the historic town of Ghent following weeks of unrelenting drought.
Much of Western Europe has experienced a season of extreme weather that scientists link to human-made climate change.
Amid the storm warnings, French President Emmanuel Macron postponed an event Wednesday on the French Riviera to mark the 78th anniversary of a key Allied invasion of Nazi-occupied France. It was rescheduled for Friday.
The dramatic downpours put an end to weeks of historic heat that left much of France parched, rivers dry and dozens of villages without running water.
Across much of Europe this summer, a series of heat waves has compounded a critical drought, creating prime wildfire conditions.
Rainfall in recent days has eased the burden on firefighters facing France’s worst fire season in the past decade, though emergency authorities said scattered wildfires continued to burn Wednesday in southwest France.


Taliban kill one of their ex-leaders from minority Hazara community

Taliban kill one of their ex-leaders from minority Hazara community
Updated 17 August 2022

Taliban kill one of their ex-leaders from minority Hazara community

Taliban kill one of their ex-leaders from minority Hazara community
  • Mawlawi Mahdi was shot dead by Taliban forces near the border with Iran as he attempted to flee the country
  • The Hazara, native to Afghanistan’s central mountains, are the country’s largest mainly Shiite ethnic group

KABUL: The Taliban killed one of their former leaders who was known as the first commander of the group hailing from the minority Shiite Hazara community, officials confirmed on Wednesday, adding that he had rebelled against the de facto government.
Mawlawi Mahdi was shot dead by Taliban forces near the border with Iran as he attempted to flee the country, the defense ministry said in a statement.
Mahdi’s appointment as a commander some years ago was touted as an example of the Taliban’s changed on stance on minorities. He was in the spotlight after the Taliban took control of Afghanistan in the wake of the pullout of western forces last year.
The Taliban are hard-line followers of the Sunni branch of Islam, and were previously almost exclusively associated with the Pashtun ethnicity. More recently, the group had sought to include members of other ethnicities and some Shiites.
The Hazara, native to Afghanistan’s central mountains, are the country’s largest mainly Shiite ethnic group. After the Taliban formed a government last year, Mahdi was given the post of intelligence chief in a central province.
The origins of the breach between Mahdi and the Taliban have not been made public, but as far back as June, the defense ministry had spoken of a clearance operation against rebels in northern Afghanistan.
The defense ministry on Wednesday described Mahdi as a the “leader of the rebels” in a district in the northern province of Sar-e-Pol.
A Taliban source told Reuters that Mahdi had fallen out with the Taliban and had revolted against the group’s leadership.
The statement said he was killed in Herat close to the border with Shiite majority Iran, where he was trying to flee.
Reuters was not able to contact representatives of Mahdi for comment.