LOS ANGELES: Hollywood heart-throb Johnny Depp suffered the worst box-office debut of his career while “Captain America: The Winter Soldier” maintained its grip on North American theaters, final figures showed Monday.

Despite being one of the highest paid actors in Tinseltown, Depp’s star power was unable to save $100 million science-fiction thriller “Transcendence” from crashing with just $10.9 million on its opening to take fourth spot.

It was the latest in a series of poor openings for movies starring Depp, coming hard on the heels of “The Lone Ranger,” “Dark Shadows” and “The Rum Diary.”

The film, which sees Depp play a scientist who escapes death when his brain is uploaded into a huge computer, was the actor’s lowest-grossing opening since 2004’s “Secret Window,” which took $18.2 million.

While Warner Bros. were left picking over the ashes of “Transcendence,” Disney toasted another solid weekend from “Captain America.”

The latest big-screen adventures of the iconic Marvel superhero, starring Chris Evans, took in $25.6 million, figures from box office tracker Exhibitor Relations said.

The film has earned more than $200 million in North America since its debut earlier in the month, when it had the biggest April opening of all time.

This week’s performance meant “Captain America” held off a strong opening from “Heaven Is For Real,” starring Greg Kinnear as the father of a four-year-old boy who wakes up from emergency surgery with a story about going to heaven and back. It raked in $22.5 million for second place.

Third spot was taken by animated children’s movie “Rio 2,” a follow-up to the 2011 hit about a family of blue macaw parrots.