NEW YORK: Grady Sizemore hit a three-run homer in the sixth inning and the Boston Red Sox finally gave Jon Lester enough run support for his first win of the year, 4-2 over the New York Yankees on Friday night.

Jonny Gomes homered leading off the sixth against CC Sabathia (1-2), and the four-run inning was more than Boston had scored for Lester in his first two starts combined. Despite a 2.51 ERA coming in, Lester (1-2) was at risk of falling to 0-3 for the first time in his career.

The left-hander was lifted with two outs in the seventh after Kelly Johnson singled to pull the Yankees within two runs. Junichi Tazawa relieved with runners at the corners and retired Derek Jeter on a flyout.

Lester allowed Alfonso Soriano's homer starting the second and six hits overall. He improved to 12-5 in 27 starts against New York.

Edward Mujica was perfect in the ninth for his first save with Boston. Red Sox closer Koji Uehara was bothered by shoulder stiffness before the game and was held out as a precaution.

Blue Jays 2 Orioles 0: In Baltimore, Dustin McGowan allowed five hits over 6 1-3 innings to earn his first win since 2008, and Toronto used two unearned runs to beat Chris Tillman and Baltimore.

Making his second start since September 2011, the oft-injured McGowan (1-1) walked one, hit two batters and struck out two. He had faced the Orioles 13 times previously — going 0-3 with a 6.99 ERA in 37 1-3 innings.

Rangers 1 Astros 0, 12 innings: In Arlington, Texas, Yu Darvish took a perfect game into the sixth inning and Texas finally finished off Houston on Robinson Chirinos' RBI single in the 12th.

Darvish retired his first 15 batters before Matt Dominguez singled softly to center. The right-hander allowed just the one hit and one walk in eight innings with nine strikeouts.

Darvish came within one out of a perfect game in Houston on April 2 last year, when Marvin Gonzalez grounded a single between the pitcher's legs. He also held the Astros hitless in Houston last Aug. 12 before Carlos Corporan's one-out homer in the eighth.







Mariners 6 Athletics 4: In Seattle, Felix Hernandez (3-0) took a shutout into the eighth and struck out 11, and Mike Zunino and Brad Miller both homered. Hernandez became the first Seattle pitcher to win three times in the first nine games of a season.

Zunino chased starter Tommy Milone (0-1) with a two-run homer in the sixth. Miller followed two batters later with a solo homer to center field with the wind blowing in.

Interleague

Padres 6 Tigers 0: In San Diego, Andrew Cashner threw his second career one-hitter and struck out a career-high 11, and Chase Headley hit a two-run homer for San Diego.

Cashner took a no-hitter into the sixth inning before Rajai Davis hit a one-out flare single into center field, just past the glove of outstretched second baseman Jedd Gyorko. Davis stole second and third, and Ian Kinsler walked before Miguel Cabrera hit into a double play.

Cashner (1-1) retired 14 in a row before allowing the single. He walked two.

Rays 2 Reds 1: In Cincinnati, David Price took a shutout into the ninth and Matt Joyce homered, helping Tampa Bay earn its first victory in Cincinnati.

The teams have a brief and lopsided interleague history. The Reds had won eight of their nine previous games, with Tampa Bay's only win coming at Tropicana Field on June 28, 2011, on Evan Longoria's game-ending homer.