DETROIT: Chris Tillman outpitched Justin Verlander, allowing one run while working into the ninth, as the Baltimore Orioles beat the Detroit Tigers 3-1 on Sunday, handing Major League Baseball's last undefeated team its first loss.

Tillman (1-0) gave up five hits, including Torii Hunter's solo homer in the fourth, in 8 1-3 innings. Tommy Hunter entered with one out in the ninth and Victor Martinez on second base and retired the last two batters for his second save.

Verlander (0-1) gave up two runs on five hits and two walks over eight innings. He struck out three, moving past Tommy Bridges into fourth place on the Tigers' all-time list with 1,674 in his career.

In other American League games, Texas' Yu Darvish allowed seven hits over seven innings in his season debut and Elvis Andrus hit a two-run homer to lead the Rangers past the Tampa Bay Rays 3-0.

Darvish (1-0) struck out six and walked one. Sidelined by neck stiffness, it was his first outing since a spring training game on March 16.

The Japanese star got his 500th career strikeout, coming in 401 2-3 innings, by fanning David DeJesus and Wil Myers in the first. According to the Rangers, it is the fewest innings for a starter to reach 500 strikeouts in MLB history.

The Yankees' CC Sabathia pitched six innings for his first victory of the season as New York topped the Toronto Blue Jays 6-4.

Sabathia (1-1) allowed four runs and seven hits, walked none and struck out six. He was hit hard in Tuesday's opening day loss at Houston, allowing six runs and eight hits, including two home runs, in six innings.

Brett Gardner hit a two-run home run for New York.

The Boston Red Sox's slow start to the season continued with a 4-0 loss to the Milwaukee Brewers.

Yovani Gallardo (2-0) made his second straight scoreless start as Milwaukee completed a three-game sweep.

The World Series champion Red Sox, who never had a losing record last year, fell to 2-4 and matched their longest skid of 2013. They were swept just once last season, in a three-game series against the Texas Rangers from May 3-5.

The Red Sox have lost their first three home games for the first time since 1984.

In Cleveland, Chris Colabello drove in four runs, Brian Dozier scored three times and Minnesota outslugged Cleveland for a 10-7 victory.

Colabello, who played seven seasons of independent ball in Canada before signing with the Twins in 2012, broke a 6-6 tie with a three-run double in the sixth inning off Blake Wood (0-1). The 30-year-old Colabello leads the AL with 11 RBIs after six games.

Joe Mauer had three hits and scored twice for the Twins, who took two of three in the series and will play their home opener Monday against Oakland.

Anthony Swarzak (1-0) picked up the win in relief of Ricky Nolasco. Glen Perkins worked a perfect ninth for his second save.

David Murphy had four hits, Jason Kipnis had three RBIs and Yan Gomes hit a two-run homer for Cleveland.

Scott Feldman threw seven strong innings, five Astros homered, and Houston snapped a three-game losing streak 7-4 at home.

Feldman (2-0) did not allow a hit until two outs in the fourth, when Josh Hamilton dribbled one toward first base that went under the glove of Feldman, who charged at it off the mound.

The right-hander allowed his first run in 11 1-3 innings this season in the fifth on a groundout to second by Erick Aybar that cut the lead to 4-1.

Chad Qualls got the last two outs for his first save of the season.

Jason Castro, Matt Dominguez, Jesus Guzman and Alex Presley homered off Jered Weaver (0-2). Jonathan Villar added a two-run shot in the seventh off Matt Shoemaker.

Jim Johnson struck out two and closed it out after losing back-to-back outings to begin with his new team, saving Oakland's victory, 6-3 against Seattle Mariners.

Brandon Moss hit a three-run homer, Yoenis Cespedes connected in the eighth and Josh Donaldson beat out an infield single in the fifth to drive in the go-ahead run.

Sonny Gray (1-0) allowed one earned run and six hits, struck out three and walked two in six innings. In the ninth, manager Bob Melvin went back to Johnson, who delivered his first save despite allowing two baserunners.