Top-seeded Marion Bartoli of France, No. 3 seed Lucie Safarova of the Czech Republic and fifth-seeded American Melanie Oudin all won in straight sets.
Canadian Valerie Tetreault also moved on, upsetting No. 4 seed Barbora Zahlavova Strycova of the Czech Republic 6-3, 3-6, 6-2 in the $220,000 WTA Tour event at the Club Avantage Multi-Sports de Quebec.
In Guangzhou, China, Sania Mirza of India ousted third-seeded Akgul Amanmuradova of Uzbekistan 6-4, 6-3 Wednesday in a day of upsets in the second round of the Guangzhou International.
Mirza broke her opponent four times while losing serve just once.
Fifth-seeded Chang Kai-Chen of Taiwan and No. 8 Chanelle Scheepers of South Africa were also eliminated. Chang lost 1-6, 6-2, 6-4 to Chinese wild card Han Xinyun, while Scheepers was routed 6-1, 6-0 by unseeded Zhang Shuai of China.
Alla Kudryavtseva of Russia also advanced, beating compatriot Ekaterina Ivanova 6-4, 3-6, 6-2.
Meantime, Zheng Jie of China will have surgery to repair an injury to her left wrist and is likely out for the rest of the year.
Tournament organizers said Wednesday that Zheng has withdrawn from next week’s China Open in Beijing. She will fly back to the United States for surgery. The 23rd-ranked Zheng is expected to be out for three to six months.
Her injury got worse during the US Open in New York. She was knocked out in the second round by Ana Ivanovic, but reached the semifinals in doubles.
