Boston beat Minnesota in the final three games of a four-game series, and won for the 11th time in 12 games in Fenway Park.
The Red Sox closed out their longest homestand of the season at 6-5.
Hideki Okajima (1-0) pitched two innings, getting out of a two-on, one-out jams in each, for the win.
Jed Lowrie drew a one-out walk against Jim Hoey (0-1) and Iglesias pinch ran. Crawford lofted one off The Wall and Iglesias slid in just ahead of the throw from short left by shortstop Matt Tolbert , knocking catcher Rene Rivera over as he scored.
In Toronto, Max Scherzer won his sixth consecutive decision, Victor Martinez hit a two-run homer and Detroit beat Toronto.
Scherzer (6-0) has not lost in eight starts this season. His season-opening winning streak is the longest by a Tigers pitcher since Jeremy Bonderman won eight straight in 2007.
Scherzer allowed two runs and five hits in five innings, matching his shortest start of the year. He walked three and struck out five.
Martinez went 3 for 4 with three RBIs and Austin Jackson had four RBIs for the Tigers, who have won six of seven to even their record at 18-18.
Toronto lost for the seventh time in nine games and dropped a season-high five games below .500.
Blue Jays right-hander Brandon Morrow (1-2), who had allowed just one hit and one walk through the first three innings, fell apart in the fourth, when the Tigers scored six runs and sent 10 batters to the plate.
In Arlington, Texas, Trevor Cahill pitched seven strong innings to earn his sixth straight win to start the season and Josh Willingham homered and drove in five runs and Oakland beat Texas.
Cahill (6-0) matched the major league lead with his sixth victory, and equaled his career best by winning his seventh consecutive decision. The 23-year-old right-hander struck out seven, walked one and allowed five hits. He became Oakland’s first 6-0 starter in 21 years.
Willingham, in the Oakland lineup after appealing his one-game suspension for making contact with an umpire, hit a three-run homer in the third put the Athletics ahead to stay.
C.J. Wilson (4-2), coming off a complete game victory at Seattle last Wednesday, allowed only two hits over seven innings. But the left-hander walked five and hit another batter — and those accounted for four of the five runs against him. He struck out two.
In Anaheim, California, Edwin Jackson pitched seven superb innings for his first victory in more than a month, Carlos Quentin homered and drove in five runs, and Chicago routed Los Angeles.
Jackson (3-4) scattered five hits, struck out five and walked one after going winless in his previous five starts since beating Tampa Bay 5-1 on April 7.
Gordon Beckham and Alexei Ramirez also homered for the White Sox, who have won three straight for the first time this season.
After the game, the Angels put left fielder Vernon Wells on the 15-day disabled list. Wells strained his groin while running out a grounder. Ervin Santana (1-4) gave up five runs and eight hits in six-plus innings, including Beckham’s two-run homer in the second and Ramirez’s leadoff drive in the seventh.
