Dawkins hit seven 3-pointers to help the Blue Devils (16-2, 4-0 Atlantic Coast Conference) build a huge lead that was never seriously threatened.
Ryan Kelly finished with 20 points and 10 rebounds for Duke, which shot 54 percent in claiming its fourth straight win in the series.
The Blue Devils moved within one victory of the school record for consecutive home victories and will match the mark if they beat Florida State on Saturday.
C.J. Harris had 20 points for Wake Forest (10-8, 1-3), which was coming off a 36-point home loss to North Carolina State and lost its third straight and fourth in five games.
In Blacksburg, Harrison Barnes scored nine of his 27 points during a 19-0 second-half run and North Carolina bounced back from a 33-point loss at Florida State.
John Henson added 16 points, 16 rebounds and six blocks for the Tar Heels (16-3, 3-1 Atlantic Coast Conference), who trailed 44-36 before Barnes started the run with two free throws, a jumper and a dunk. Before it was over, it stretched to 31-5 and a 67-49 lead with 8:23 remaining.
The Hokies (11-7, 0-4) missed 15 straight shots during the run and lost their fourth straight. They are off to their first 0-4 start in league play since the 2006 team lost its first six.
Erick Green led Virginia Tech with 17 points and Dorenzo Hudson had 16, all in a span of less than 8 minutes in the first half.
The Tar Heels trailed 39-34 at halftime.
In Atlanta, Mike Scott scored 18 points and Virginia bounced back from a tough loss at Duke.
The Cavaliers (15-2, 2-1 Atlantic Coast Conference) were never seriously challenged by the Yellow Jackets, who put up their lowest-scoring game since a 53-38 loss to Wake Forest on Feb. 6, 1982, during Bobby Cremins' first season as coach.
Virginia was coming off a 61-58 defeat at Cameron Indoor Stadium that snapped a 12-game winning streak.
Kammeon Holsey had 12 points to lead Georgia Tech (8-10, 1-3), which shot 29 percent (14 of 48) from the field, including 1 of 15 from 3-point range, and lost for the sixth time in seven games.
The Cavaliers have won five straight over the Yellow Jackets and six of the last seven. Virginia is off to its best start since beginning 15-2 during 1982-83 - Ralph Sampson's senior year. This was the Cavaliers' largest margin against an ACC opponent since a 104-72 win over North Carolina State in 1991.
In State College, Tim Frazier hit a floater in the lane with 8 seconds left and Jermaine Marshall blocked Sam Maniscalco's layup at the buzzer to give Penn State the upset win.
Frazier finished with 12 points and nine assists for the Nittany Lions (10-10, 2-5 Big Ten), who ended a three-game losing skid.
Off a timeout, Frazier drove at the top of the key before Jon Graham's pick freed him from hounding defender Brandon Paul.
The Illini (15-4, 4-2) lost for the first time since re-entering the AP Top 25 this week. They had a short stay atop the Big Ten as the league's lone one-loss team in conference play.
Paul had 20 points to pace the Illini, while Meyers Leonard added 15.
Cammeron Woodyard finished with 17 points for Penn State, while Marshall finished with seven points and five rebounds.
In Moraga, California, Rob Jones had 17 points and 10 rebounds and Matthew Dellavedova scored 13 points to lead Saint Mary's to its eighth straight victory.
Stephen Holt added 12 points and three assists to help the Gaels (18-2, 7-0) remain the only unbeaten team in the West Coast Conference. Saint Mary's has won 16 of 17 since a loss at No. 3 Baylor on Dec. 22.
Caleb Willis had 14 points and Jordan Baker added 13 for Pepperdine (7-11, 1-6), losers of six straight and still searching for its first conference road win of the season. Corbin Moore had 15 rebounds for the Waves.
Dellavedova and Holt made consecutive 3-pointers to put the Gaels ahead 59-44 with 5:56 remaining. Saint Mary's outshot Pepperdine 42.6 percent to 40.9 percent.
