INDIAN WELLS, United States: Australian Open champion Angelique Kerber, fourth seed Garbine Muguruza and Spanish star Carla Suarez Navarro were all second-round casualties at the Indian Wells hardcourt tennis tournament on Saturday.

World No. 2 and second seed Kerber crashed out of the joint WTA and ATP event, losing her opening match in straight sets 7-5, 7-5 to Czech Denisa Allertova.

Former Wimbledon finalist Muguruza was upset by American Christina McHale 7-5, 6-1 and sixth seeded Suarez Navarro withdrew from the tournament with a right ankle injury just prior to her opening match against Daria Kasatkina.

Kerber knocked off Serena Williams in the Australian Open final in January for the first Grand Slam tournament victory of her career.

But Kerber’s biggest problem on the WTA Tour has been inconsistency. She played superbly in Australia but then lost her first match at Doha. This is the third straight year she has lost her opening match at Indian Wells.

In other women’s matches, seventh seeded Belinda Bencic of Switzerland beat American Laura Davis 6-3, 3-6, 6-3, Eugenie Bouchard beat Sloane Stephens 7-5, 7-5 and Italian Roberta Vinci outlasted Margarita Gasparyan 6-3, 6-7 (7/9), 7-6 (7/5).

On the men’s side of the draw, world No. 2 and second seed Andy Murray got his campaign off to a flying start with a 6-4, 7-6 (7/3) win over Spaniard Marcel Granollers.

Murray is playing in his fifth ATP Tour tournament since losing to Novak Djokovic in the final of the Australian Open. It was his fourth championship match loss to Djokovic and the fifth time he has lost in an Australian final.

Murray, who was the Indian Wells runner-up to Rafael Nadal in 2009, advances to the third round where he will face Federico Delbonis who beat Joao Sousa 7-6 (8/6), 6-4.

“I came out and served a good game,” Murray said. “I had my service game going, especially in the tiebreaker.”

French Open champion Stan Wawrinka defeated Illya Marchenko 6-3, 6-2 to reach the third round.

Third seed Wawrinka, who will turn 31 later this month, moves on to face unseeded Russian Andrey Kuznetsov who beat Jeremy Chardy in straight sets 6-4, 6-2.

Czech Tomas Berdych defeated Juan Martin del Potro 7-6 (7/4), 6-2 and Canadian 12th seed Milos Raonic routed Inigo Cervantes-Huegun 6-1, 6-3.

Eighth seeded Richard Gasquet beat Nicolas Mahut 6-4, 6-1 in an all-French matchup and Gael Monfils.