Green Falcons prepare for friendlies against Venezuela, Bolivia in March

Green Falcons prepare for friendlies against Venezuela, Bolivia in March
The matches are the next stage in the Green Falcons’ preparatory program for March. Credit: @SaudiNT
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Updated 28 February 2023

Green Falcons prepare for friendlies against Venezuela, Bolivia in March

Green Falcons prepare for friendlies against Venezuela, Bolivia in March
  • The first match will be on March 24 against Venezuela, and the second against Bolivia on March 28

Riyadh: The Saudi national football team are gearing up for friendly matches against Venezuela and Bolivia in the coastal city of Jeddah in March.

The matches are the next stage in the Green Falcons’ preparatory program for March.

The national team’s management announced the establishment of a preparatory camp in the city for squad members from March 20-28.

The first match will be on March 24 against Venezuela, and the second against Bolivia on March 28. Both matches will be held at Prince Abdullah Al-Faisal Stadium.


Novartis drug cuts recurrence risk by 25 percent in early-stage breast cancer

Novartis drug cuts recurrence risk by 25 percent in early-stage breast cancer
Updated 9 min 58 sec ago

Novartis drug cuts recurrence risk by 25 percent in early-stage breast cancer

Novartis drug cuts recurrence risk by 25 percent in early-stage breast cancer
  • The company on Friday said the relative risk reduction of cancer recurrence was 25.2%
  • The results were broadly consistent regardless of patients' menopausal status or cancer progression status

FRANKFURT: Novartis breast cancer drug Kisqali cut the risk of recurrence by more than 25 percent in a pivotal trial on women diagnosed at an early stage, positioning the Swiss drugmaker to win new patients and but facing strong competition from Eli Lilly.
The company on Friday said the relative risk reduction of cancer recurrence was 25.2 percent and that the results were broadly consistent regardless of patients’ menopausal status or cancer progression status. The results were presented at the annual meeting of the American Society of Clinical Oncology in Chicago.
The Swiss drugmaker’s shares rose, even as the efficacy read-out fell short of that of a drug by Lilly, but a more favorable side effect profile might swing the balance in favor of Kisqali.
The drug was used in the trial together with standard endocrine therapy to treat a type of cancer that grows in response to hormones and it was compared to endocrine therapy alone.
The Novartis treatment has been approved to treat hormone-driven breast cancer that has spread to other parts of the body, where Novartis has taken market share from Pfizer’s Ibrance.
But an earlier diagnosis, when tumors can still be surgically removed, is much more common, representing about 90 percent of patients.
Still, better drugs are needed after surgery because the cancer later returns in between a third and one half of cases.
Eli Lilly is ahead with the approval of rival drug Verzenio in the early setting. But that is in a subset of women who are at high risk of recurrence after surgery, typically diagnosed based on signs of cancer in the lymph nodes.
Here, Novartis will face tough competition because the US drugmaker has said Verzenio reduces the risk of recurrence by 35 percent in that group.
But Kisqali looks set to be a pioneer in a wider market because it was tested successfully in both high-risk and medium-risk patients, a population that is twice as large.
Analysts have said investors could be disappointed if the Kisqali read-out fell well short of Verzenio’s efficacy and Jefferies analysts said on Friday the efficacy read-out was “closer to our downside scenario.”
But Novartis stressed very low rates of symptomatic side effects in its trial, important to patients facing years-long treatment, with severe diarrhea affecting only 0.6 percent of participants on Kisqali.
That compares with 8 percent-20 percent of the women in trials with Eli Lilly’s Verzenio being affected by severe diarrhea.
“This may be very relevant commercially,” said Evercore ISI analyst Umer Raffat.
Novartis shares were up 1.5 percent at 1430 GMT, rebounding from initial losses after the news. Lilly shares gained 0.9 percent.
“We know diarrhea can be a very troublesome, burdensome adverse event for patients taking anti-cancer medicines,” said Jeff Legos, Head of Oncology & Hematology Development at Novartis.
The March trial update boosted market confidence in targets issued by CEO Vas Narasimhan for annual sales growth of 4 percent through 2027 and a core operating income margin of 40 percent from 2027, analysts have said.
Novartis will request approval for wider use in the US and Europe before the end of the year, it added.
Novartis gave a brief preview of the Kisqali data in March, boosting its shares and growth prospects.


José Mourinho charged by UEFA for verbally abusing referee at Europa League final

José Mourinho charged by UEFA for verbally abusing referee at Europa League final
Updated 26 min 24 sec ago

José Mourinho charged by UEFA for verbally abusing referee at Europa League final

José Mourinho charged by UEFA for verbally abusing referee at Europa League final
  • UEFA said the Roma coach is charged for “insulting / abusive language against a match official” after Sevilla’s victory in Budapest this week
  • Footage circulated Thursday of Mourinho approaching referee Anthony Taylor in the garage and calling him a “disgrace” with an expletive

NYON, Switzerland: José Mourinho was charged by UEFA on Friday after being filmed aggressively cursing at the English match referee in a stadium garage after the Europa League final.
UEFA said the Roma coach is charged for “insulting / abusive language against a match official” after Sevilla’s victory in Budapest this week.
It was one of a slew of disciplinary charges UEFA opened into incidents at a testy, bad-tempered game that lasted more than three hours on Wednesday.
Footage circulated Thursday of Mourinho approaching referee Anthony Taylor in the garage and calling him a “disgrace” with an expletive.
Later Thursday, Taylor and his family were harassed and verbally abused by Roma fans at the airport in Budapest.
Roma lost to Sevilla in a penalty shootout after a 1-1 draw that saw players and officials clash on the field and in the technical area.
UEFA charged both teams with improper conduct – typically activated for at least five yellow cards shown – and Roma was charged over crowd disturbances and acts of damage.
Sevilla was also charged because dozens of its fans invaded the field after the match.
UEFA gave no timetable for its disciplinary panel to judge the cases.


Break in case of emergency: Japanese vending machine to offer free food if earthquake hits

Break in case of emergency: Japanese vending machine to offer free food if earthquake hits
Updated 02 June 2023

Break in case of emergency: Japanese vending machine to offer free food if earthquake hits

Break in case of emergency: Japanese vending machine to offer free food if earthquake hits
  • Coastal city launches trial of lifesaving devices that will distribute essential supplies in case of disaster

LONDON: Imagine a city with vending machines that unlock during earthquakes and other natural disasters, providing free food and supplies.

That is exactly what is happening in the Japanese coastal city of Ako, in Hyogo prefecture, as the country steps up its natural disaster preparations.

On Friday, Japanese news outlet The Mainichi reported that the city had launched a trial run with two emergency vending machines.

The machines usually sell snacks and drinks, but will also distribute items for free during major earthquakes or typhoons.

As well as 300 bottles of soda and 150 emergency food items, the lifesaving machines contain lockers filled with essential sanitary items, such as portable toilets and masks, the news outlet said.

The vending machines unlock when an evacuation order is issued after a quake or other natural disasters.

The “hygiene supply disaster prevention stockpiling vending machines” have been installed near buildings designated as evacuation shelters.

Ako is located in an area that is vulnerable to severe earthquakes. 

The emergency vending machine project is a collaboration between the municipality and Tokyo-based pharmaceutical firm Earth Corp., which has research and production facilities in Ako.

The company has signed agreements with 17 municipalities across Japan since 2020 to help solve local issues, with the machines in Ako said to be the first of their type in the country.

A company representative said: “We would like to spread this throughout the country as a socially oriented project.”

Vending machines can be found on almost every street in Japanese cities and sell a wide variety of items —  some as unique as bear or whale meat.

In a similar initiative, a vending machine with a radio that automatically broadcasts emergency information was installed in a Tokyo park earlier this year.

The radio will be activated by severe earthquakes, and transmit evacuation and other vital information from a local community station.

Japan is one of the most earthquake-prone countries in the world. On May 26, a 6.2 magnitude quake struck east of Tokyo.


Iran frees one Danish, two Austrian-Iranian citizens

Iran frees one Danish, two Austrian-Iranian citizens
Updated 02 June 2023

Iran frees one Danish, two Austrian-Iranian citizens

Iran frees one Danish, two Austrian-Iranian citizens
  • Belgian Prime Minister Alexander De Croo informed the governments of Denmark and Austria of the release

BRUSSELS: Iran on Friday released one Danish and two Austrian-Iranian citizens it had been holding after mediation by Oman, and they are being flown to Belgium, Belgian Prime Minister Alexander De Croo said.
He added that he had informed the governments of Denmark and Austria of the release, which came a week after Tehran freed a Belgian aid worker in exchange for an Iranian diplomat who was convicted on terrorism charges.


Ukraine’s Zelensky: NATO membership ‘impossible’ until Russia war ends

Ukraine’s Zelensky: NATO membership ‘impossible’ until Russia war ends
Updated 02 June 2023

Ukraine’s Zelensky: NATO membership ‘impossible’ until Russia war ends

Ukraine’s Zelensky: NATO membership ‘impossible’ until Russia war ends
  • Western governments are wary of any move that might take the alliance closer to war with Russia

KYIV: President Volodymyr Zelensky said on Friday he knew it would be “impossible” for Ukraine to join NATO while Russia was waging war on his country.
Zelensky has pressed for Ukrainian membership of the military alliance but allies are divided over how fast that should happen. Western governments are wary of any move that might take the alliance closer to war with Russia.
In a joint briefing in the Ukrainian capital with Estonian President Alar Karis, he said joining the alliance was still the best security guarantee for Kyiv.
“But we are adequate people and understand that we will not pull any NATO country into a war,” Zelensky said. “And that’s why we understand that we won’t be a member of NATO while this war is ongoing. Not because we don’t want to, because it’s impossible.”